CRISPR/Cas9-Mediated Treatment Ameliorates the Phenotype of the Epidermolytic Palmoplantar Keratoderma-like Mouse.

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作者： Xiao-Rui,Luan ^[1] ; Xiao-Ling,Chen ^[2] ; Yue-Xiao,Tang ^[1] ; Jin-Yan,Zhang ^[1] ; Xiang,Gao ^[3] ; Hai-Ping,Ke ^[4] ; Zhao-Yu,Lin ^[3] ; Xian-Ning,Zhang ^[5]

作者单位： Department of Genetics, Research Center for Molecular Medicine, Institute of Cell Biology, Key Laboratory of Reproductive Genetics, Ministry of Education, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058, China. ^[1] Department of Biological Chemistry, Zhejiang Chinese Medical University, Hangzhou, Zhejiang 310053, China. ^[2] Key Laboratory of Model Animals for Disease Study of The Ministry of Education, Model Animal Research Center of Nanjing University, Nanjing, Jiangsu 210061, China. ^[3] Department of Biology, Ningbo College of Health Sciences, Ningbo, Zhejiang 315100, China. ^[4] Department of Genetics, Research Center for Molecular Medicine, Institute of Cell Biology, Key Laboratory of Reproductive Genetics, Ministry of Education, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058, China. Electronic address: zhangxianning@zju.edu.cn. ^[5]

关键词 CRISPR/Cas9 Krt9 gene (mouse)epidermolytic palmoplantar keratoderma gene therapy indel

DOI 10.1016/j.omtn.2018.05.005

PMID 30195761

发布时间 2021-01-09

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Molecular therapy. Nucleic acids

2018年12卷

220-228页

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CRISPR/Cas9-Mediated Treatment Ameliorates the Phenotype of the Epidermolytic Palmoplantar Keratoderma-like Mouse.

Molecular therapy. Nucleic acids

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Molecular therapy. Nucleic acids

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CRISPR/Cas9-Mediated Treatment Ameliorates the Phenotype of the Epidermolytic Palmoplantar Keratoderma-like Mouse.

Molecular therapy. Nucleic acids

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Molecular therapy. Nucleic acids

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