换一批Coordinate regulation of mutant NPC1 degradation by selective ER autophagy and MARCH6-dependent ERAD.
第一作者：
Mark L,Schultz
第一单位：
Department of Pathology, University of Michigan School of Medicine, Ann Arbor, MI, 48109, USA.
作者：
医学主题词
动物(Animals);自噬(Autophagy);脑(Brain);载体蛋白质类(Carrier Proteins);内质网(Endoplasmic Reticulum);成纤维细胞(Fibroblasts);纯合子(Homozygote);人类(Humans);细胞内信号肽和蛋白质类(Intracellular Signaling Peptides and Proteins);溶酶体(Lysosomes);膜糖蛋白类(Membrane Glycoproteins);膜蛋白质类(Membrane Proteins);小鼠(Mice);突变蛋白质类(Mutant Proteins);突变(Mutation);蛋白酶体内肽酶复合物(Proteasome Endopeptidase Complex);蛋白质转运(Protein Transport);蛋白质类(Proteins);泛素蛋白连接酶类(Ubiquitin-Protein Ligases);长春碱(Vinblastine)
DOI
10.1038/s41467-018-06115-2
PMID
30202070
发布时间
2021-12-04
基金项目
R35 GM130292/GM/NIGMS NIH HHS/United States
R01 DK120047/DK/NIDDK NIH HHS/United States
R01 GM113188/GM/NIGMS NIH HHS/United States
R01 NS085054/NS/NINDS NIH HHS/United States
R37 AG021904/AG/NIA NIH HHS/United States
T32 GM007863/GM/NIGMS NIH HHS/United States
T32 NS007222/NS/NINDS NIH HHS/United States
P30 AG038072/AG/NIA NIH HHS/United States
R01 NS063967/NS/NINDS NIH HHS/United States
P01 AG031782/AG/NIA NIH HHS/United States
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