The Bisindole Alkaloid Caulerpin, from Seaweeds of the Genus <i>Caulerpa</i>, Attenuated Colon Damage in Murine Colitis Model.-论文-万方医学网

第一作者： Alessandra M M,Lucena

第一单位： Department of Microbiology and Parasitology, Federal University of Rio Grande do Norte, Avenida Salgado Filho, BR 101, Campus Universitario, Lagoa Nova, Natal, RN 59078-900, Brazil. ale.marinho@hotmail.com.

作者： Alessandra M M,Lucena ^[1] ; Cássio R M,Souza ^[2] ; Jéssica T,Jales ^[3] ; Paulo M M,Guedes ^[4] ; George E C,de Miranda ^[5] ; Adolpho M A,de Moura ^[6] ; João X,Araújo-Júnior ^[7] ; George J,Nascimento ^[8] ; Kátia C,Scortecci ^[9] ; Barbara V O,Santos ^[10] ; Janeusa T,Souto ^[11]

作者单位： Department of Microbiology and Parasitology, Federal University of Rio Grande do Norte, Avenida Salgado Filho, BR 101, Campus Universitario, Lagoa Nova, Natal, RN 59078-900, Brazil. ale.marinho@hotmail.com. ^[1] Department of Microbiology and Parasitology, Federal University of Rio Grande do Norte, Avenida Salgado Filho, BR 101, Campus Universitario, Lagoa Nova, Natal, RN 59078-900, Brazil. cassiormsouza@gmail.com. ^[2] Department of Microbiology and Parasitology, Federal University of Rio Grande do Norte, Avenida Salgado Filho, BR 101, Campus Universitario, Lagoa Nova, Natal, RN 59078-900, Brazil. jessica_jales@hotmail.com. ^[3] Department of Microbiology and Parasitology, Federal University of Rio Grande do Norte, Avenida Salgado Filho, BR 101, Campus Universitario, Lagoa Nova, Natal, RN 59078-900, Brazil. guedespmm@gmail.com. ^[4] Laboratory of Marine Algae, Department of Systematics and Ecology, Federal University of Paraiba, Joao Pessoa, PB 58051-900, Brazil. mirandag@dse.ufpb.br. ^[5] Laboratory of Animal Experimentation of the Institute of Immunobiological Technology (LAEAN/Bio-Manguinhos), Rio de Janeiro, RJ 21040-900, Brazil. adolpho.moura@bio.fiocruz.br. ^[6] School of Nursing and Pharmacy, Federal University of Alagoas, Maceió, AL 57072-900, Brazil. jotaaraujo2004@gmail.com. ^[7] Academic Unit of Biological Sciences, Federal University of Campina Grande, Patos, PB 58708-110, Brazil. geonascimento79@yahoo.com.br. ^[8] Department of Cell Biology and Genetics, Federal University of Rio Grande do Norte, Avenida Salgado Filho, BR 101, Campus Universitario, Lagoa Nova, Natal, RN 59078-900, Brazil. kacscort@yahoo.com. ^[9] Postgraduate Program in Natural Products and Synthetic Bioactive and Department of Pharmaceutical Sciences, Federal University of Paraíba, João Pessoa, PB 58051-900, Brazil. barbara@ltf.ufpb.br. ^[10] Department of Microbiology and Parasitology, Federal University of Rio Grande do Norte, Avenida Salgado Filho, BR 101, Campus Universitario, Lagoa Nova, Natal, RN 59078-900, Brazil. jtsouto@cb.ufrn.br. ^[11]

主题词生物碱类(Alkaloids);动物(Animals);消炎药(Anti-Inflammatory Agents);蕨藻属(Caulerpa);结肠炎, 溃疡性(Colitis, Ulcerative);结肠(Colon);细胞因子类(Cytokines);硫酸葡聚糖(Dextran Sulfate);疾病模型, 动物(Disease Models, Animal);剂量效应关系, 药物(Dose-Response Relationship, Drug);药物评价, 临床前(Drug Evaluation, Preclinical);人类(Humans);吲哚类(Indoles);肠黏膜(Intestinal Mucosa);男(雄)性(Male);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);腹膜炎(Peritonitis);海藻(Seaweed);治疗结果(Treatment Outcome);酵母多糖(Zymosan)

DOI 10.3390/md16090318

PMID 30205459

发布时间 2019-02-15

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The Bisindole Alkaloid Caulerpin, from Seaweeds of the Genus <i>Caulerpa</i>, Attenuated Colon Damage in Murine Colitis Model.

Marine drugs

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The Bisindole Alkaloid Caulerpin, from Seaweeds of the Genus <i>Caulerpa</i>, Attenuated Colon Damage in Murine Colitis Model.

Marine drugs

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Marine drugs

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