Bone marrow-specific loss of <i>ABI1</i> induces myeloproliferative neoplasm with features resembling human myelofibrosis.
第一作者:
Anna,Chorzalska
第一单位:
Signal Transduction Laboratory, Division of Hematology/Oncology at Rhode Island Hospital and Warren Alpert Medical School at Brown University, Providence, RI.
作者:
医学主题词
衔接蛋白质类, 信号转导(Adaptor Proteins, Signal Transducing);动物(Animals);骨髓(Bone Marrow);细胞, 培养的(Cells, Cultured);细胞支架蛋白质类(Cytoskeletal Proteins);减量调节(Down-Regulation);女(雌)性(Female);基因缺失(Gene Deletion);人类(Humans);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 转基因(Mice, Transgenic);NF-κB(NF-kappa B);原发性骨髓纤维化(Primary Myelofibrosis);STAT3转录因子(STAT3 Transcription Factor);信号传导(Signal Transduction);src族激酶类(src-Family Kinases)
DOI
10.1182/blood-2018-05-848408
PMID
30213875
发布时间
2021-02-02
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Blood
2053-2066页
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