Aspirin cooperates with p300 to activate the acetylation of H3K9 and promote FasL-mediated apoptosis of cancer stem-like cells in colorectal cancer.

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第一作者： Zhigang,Chen

第一单位： Department of Surgical Oncology, Second Affiliated Hospital and Cancer Institute (Key Laboratory of Cancer Prevention & Intervention, National Ministry of Education, Provincial Key Laboratory of Molecular Biology in Medical Sciences), Zhejiang University School of Medicine, Hangzhou, China.

作者： Zhigang,Chen ^[1] ; Wenlu,Li ^[2] ; Fuming,Qiu ^[3] ; Qi,Huang ^[1] ; Zhou,Jiang ^[1] ; Jun,Ye ^[1] ; Pu,Cheng ^[4] ; Cho,Low ^[1] ; Yikun,Guo ^[2] ; Xinchi,Yi ^[2] ; Wenteng,Chen ^[2] ; Yongpin,Yu ^[5] ; YueHua,Han ^[5] ; Jun,Wu ^[4] ; Shenghang,Jin ^[1] ; Dong,Kong ^[1] ; Jian,Huang ^[2]

作者单位： Department of Surgical Oncology, Second Affiliated Hospital and Cancer Institute (Key Laboratory of Cancer Prevention & Intervention, National Ministry of Education, Provincial Key Laboratory of Molecular Biology in Medical Sciences), Zhejiang University School of Medicine, Hangzhou, China. ^[1] Department of Neuroscience, Tufts University School of Medicine; Programs of Neuroscience and Cellular, Molecular and Development Biology, Tufts Sackler School of Graduate Biomedical Sciences, Boston, MA, USA. ^[2] Department of Pharmacy, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China. ^[3] Department of Gastroenterology, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China. ^[4] College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China. ^[5]

关键词 Aspirin FasL apoptosis cancer stem-like cells colorectal cancer