首页> Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents> Thiazoles with cyclopropyl fragment as antifungal, anticonvulsant, and anti-<i>Toxoplasma gondii</i> agents: synthesis, toxicity evaluation, and molecular docking study.

Thiazoles with cyclopropyl fragment as antifungal, anticonvulsant, and anti-<i>Toxoplasma gondii</i> agents: synthesis, toxicity evaluation, and molecular docking study.

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第一作者： Krzysztof Z,Łączkowski

第一单位： 1Department of Chemical Technology and Pharmaceuticals, Faculty of Pharmacy, Collegium Medicum, Nicolaus Copernicus University, Jurasza 2, 85-089 Bydgoszcz, Poland.

作者： Krzysztof Z,Łączkowski ^[1] ; Natalia,Konklewska ^[1] ; Anna,Biernasiuk ^[2] ; Anna,Malm ^[2] ; Kinga,Sałat ^[3] ; Anna,Furgała ^[3] ; Katarzyna,Dzitko ^[4] ; Adrian,Bekier ^[4] ; Angelika,Baranowska-Łączkowska ^[5] ; Agata,Paneth ^[6]

作者单位： 1Department of Chemical Technology and Pharmaceuticals, Faculty of Pharmacy, Collegium Medicum, Nicolaus Copernicus University, Jurasza 2, 85-089 Bydgoszcz, Poland. ^[1] 2Department of Pharmaceutical Microbiology, Faculty of Pharmacy, Medical University, Chodźki 1, 20-093 Lublin, Poland. ^[2] 3Chair of Pharmacodynamics, Faculty of Pharmacy, Jagiellonian University, Medical College, Medyczna 9, 30-688 Krakow, Poland. ^[3] 4Department of Immunoparasitology, Faculty of Biology and Environmental Protection, University of Lodz, Banacha 12/16, 90-237 Lodz, Poland. ^[4] 5Institute of Physics, Kazimierz Wielki University, Plac Weyssenhoffa 11, 85-072 Bydgoszcz, Poland. ^[5] 6Department of Organic Chemistry, Faculty of Pharmacy, Medical University of Lublin, Chodźki 4a, 20-093 Lublin, Poland. ^[6]

关键词 Anticonvulsant activity Candida spp.Cyclopropanecarboxaldehyde Thiazole Toxoplasma gondii

DOI 10.1007/s00044-018-2221-x

PMID 30220831

发布时间 2024-03-31

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