Decreased human antigen R expression confers resistance to tyrosine kinase inhibitors in epidermal growth factor receptor-mutant lung cancer by inhibiting Bim expression.
第一作者:
Yunfeng,Yao
第一单位:
Institute of Post‑Graduate, The Second Military Medical University, People's Liberation Army, Shanghai 200433, P.R. China.
作者:
医学主题词
动物(Animals);癌, 非小细胞肺(Carcinoma, Non-Small-Cell Lung);细胞系, 肿瘤(Cell Line, Tumor);减量调节(Down-Regulation);抗药性, 肿瘤(Drug Resistance, Neoplasm);女(雌)性(Female);人类(Humans);肺肿瘤(Lung Neoplasms);男(雄)性(Male);小鼠, 近交BALB C(Mice, Inbred BALB C);中年人(Middle Aged);突变(Mutation);蛋白激酶抑制剂(Protein Kinase Inhibitors)
DOI
10.3892/ijmm.2018.3835
PMID
30226552
发布时间
2019-01-21
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