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DNA polymerase ε-dependent modulation of the pausing property of the CMG helicase at the barrier.

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第一作者： Kohji,Hizume

第一单位： Division of Microbial Genetics, National Institute of Genetics, Mishima 411-8540, Japan.;Department of Genetics, School of Life Science, Graduate University for Advanced Studies (SOKENDAI), Mishima 411-8540, Japan.;Division of RI Laboratory, Biomedical Research Center, Saitama Medical University, Moroyama-machi 350-0495, Japan.

作者： Kohji,Hizume ^[1] ; Shizuko,Endo ^[2] ; Sachiko,Muramatsu ^[2] ; Takehiko,Kobayashi ^[3] ; Hiroyuki,Araki ^[4]

作者单位： Division of Microbial Genetics, National Institute of Genetics, Mishima 411-8540, Japan.;Department of Genetics, School of Life Science, Graduate University for Advanced Studies (SOKENDAI), Mishima 411-8540, Japan.;Division of RI Laboratory, Biomedical Research Center, Saitama Medical University, Moroyama-machi 350-0495, Japan. ^[1] Division of Microbial Genetics, National Institute of Genetics, Mishima 411-8540, Japan. ^[2] Institute of Quantitative Biosciences, The University of Tokyo, Tokyo 113-0032, Japan. ^[3] Division of Microbial Genetics, National Institute of Genetics, Mishima 411-8540, Japan.;Department of Genetics, School of Life Science, Graduate University for Advanced Studies (SOKENDAI), Mishima 411-8540, Japan. ^[4]

关键词 CMG helicase DNA replication Polε replication fork barrier

主题词结合部位(Binding Sites);DNA聚合酶Ⅱ(DNA Polymerase II);DNA复制(DNA Replication);DNA结合蛋白质类(DNA-Binding Proteins);真菌蛋白质类(Fungal Proteins);Lac抑制子(Lac Repressors)

DOI 10.1101/gad.317073.118

PMID 30232092

发布时间 2020-12-09

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