Hedgehog Signaling in Lung Cancer: From Oncogenesis to Cancer Treatment Resistance.

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作者： Etienne,Giroux-Leprieur ^[1] ; Adrien,Costantini ^[2] ; Vivianne W,Ding ^[3] ; Biao,He ^[4]

作者单位： Department of Respiratory Diseases and Thoracic Oncology, APHP-Hopital Ambroise Pare, 92100 Boulogne-Billancourt, France. Etienne.giroux-leprieur@aphp.fr.;EA 4340, UVSQ, Université Paris-Saclay, 92100 Boulogne-Billancourt, France. Etienne.giroux-leprieur@aphp.fr. ^[1] Department of Respiratory Diseases and Thoracic Oncology, APHP-Hopital Ambroise Pare, 92100 Boulogne-Billancourt, France. Adrien.Costantini@aphp.fr.;EA 4340, UVSQ, Université Paris-Saclay, 92100 Boulogne-Billancourt, France. Adrien.Costantini@aphp.fr. ^[2] Thoracic Oncology Program, Department of Surgery, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA 94143, USA. vivianne.ding@ucsf.edu. ^[3] Thoracic Oncology Program, Department of Surgery, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA 94143, USA. Biao.He@ucsf.edu. ^[4]

关键词 Epidermal Growth Factor Receptor (EGFR)Sonic Hedgehog cancer stem cell chemoresistance immune checkpoint inhibitor lung cancer oncogenesis radiotherapy tyrosine kinase inhibitor

主题词动物(Animals);抗药性, 肿瘤(Drug Resistance, Neoplasm);猬蛋白质类(Hedgehog Proteins);人类(Humans);肺肿瘤(Lung Neoplasms);辐射耐受性(Radiation Tolerance);信号传导(Signal Transduction)

DOI 10.3390/ijms19092835

PMID 30235830

发布时间 2024-11-13

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