Topical treatment with a transient receptor potential ankyrin 1 (TRPA1) antagonist reduced nociception and inflammation in a thermal lesion model in rats.

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第一作者： Caren Tatiane,de David Antoniazzi

第一单位： Graduated Program in Pharmacology, Federal University of Santa Maria (UFSM), 97105-900 Santa Maria, RS, Brazil.

作者： Caren Tatiane,de David Antoniazzi ^[1] ; Samira Dal-Toé,De Prá ^[2] ; Paula Ronsani,Ferro ^[2] ; Mariane Arnoldi,Silva ^[3] ; Gabriela,Adamante ^[2] ; Amanda Spring,de Almeida ^[1] ; Camila,Camponogara ^[4] ; Cássia Regina,da Silva ^[5] ; Gustavo,de Bem Silveira ^[2] ; Paulo Cesar Lock,Silveira ^[2] ; Sara Marchesan,Oliveira ^[4] ; Flávia Karine,Rigo ^[2] ; Francesco,De Logu ^[6] ; Romina,Nassini ^[6] ; Gabriela,Trevisan ^[7]

作者单位： Graduated Program in Pharmacology, Federal University of Santa Maria (UFSM), 97105-900 Santa Maria, RS, Brazil. ^[1] Graduated Program in Health Sciences, University of the Extreme South of Santa Catarina (Unesc), 88006-000 Criciúma, SC, Brazil. ^[2] Faculty META (META), 69914-220 Rio Branco, AC, Brazil. ^[3] Graduated Program in Biological Sciences: Toxicological Biochemistry, Federal University of Santa Maria (UFSM), 97105-900 Santa Maria, RS, Brazil. ^[4] Genetics and Biochemistry Institute, Federal University of Uberlândia, 38408-100 Uberlândia, MG, Brazil. ^[5] Department of Health Sciences, Section of Clinical Pharmacology and Oncology, University of Florence, Florence 50139, Italy. ^[6] Graduated Program in Pharmacology, Federal University of Santa Maria (UFSM), 97105-900 Santa Maria, RS, Brazil; Graduated Program in Health Sciences, University of the Extreme South of Santa Catarina (Unesc), 88006-000 Criciúma, SC, Brazil. Electronic address: gabriela.trevisan@ufsm.br. ^[7]

关键词 Allodynia Anti-inflammatory Burn HC-030031 Hydrogen peroxide, NADPH oxidase