Small molecule-mediated reprogramming of human hepatocytes into bipotent progenitor cells.-论文-万方医学网

第一作者： Yohan,Kim

第一单位： Department of Surgery, Hanyang University College of Medicine, Seoul 04763, Republic of Korea; HY Indang Center of Regenerative Medicine and Stem Cell Research, Hanyang University, Seoul 04763, Republic of Korea.

作者： Yohan,Kim ^[1] ; Kyojin,Kang ^[1] ; Seung Bum,Lee ^[2] ; Daekwan,Seo ^[3] ; Sangtae,Yoon ^[1] ; Sung Joo,Kim ^[4] ; Kiseok,Jang ^[5] ; Yun Kyung,Jung ^[6] ; Kyeong Geun,Lee ^[6] ; Valentina M,Factor ^[7] ; Jaemin,Jeong ^[8] ; Dongho,Choi ^[9]

作者单位： Department of Surgery, Hanyang University College of Medicine, Seoul 04763, Republic of Korea; HY Indang Center of Regenerative Medicine and Stem Cell Research, Hanyang University, Seoul 04763, Republic of Korea. ^[1] Laboratory of Radiation Exposure & Therapeutics, National Radiation Emergency Medical Center, Korea Institute of Radiological & Medical Science, Seoul 01812, Republic of Korea. ^[2] Macrogen Corporation, Rockville, MD 20850, USA. ^[3] Department of Surgery, Samsung Medical Center, Sungkyunkwan University College of Medicine, Seoul 03063, Republic of Korea. ^[4] Department of Pathology, Hanyang University College of Medicine, Seoul 04763, Republic of Korea. ^[5] Department of Surgery, Hanyang University College of Medicine, Seoul 04763, Republic of Korea. ^[6] Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA. ^[7] Department of Surgery, Hanyang University College of Medicine, Seoul 04763, Republic of Korea; HY Indang Center of Regenerative Medicine and Stem Cell Research, Hanyang University, Seoul 04763, Republic of Korea. Electronic address: jmj1103@gmail.com. ^[8] Department of Surgery, Hanyang University College of Medicine, Seoul 04763, Republic of Korea; HY Indang Center of Regenerative Medicine and Stem Cell Research, Hanyang University, Seoul 04763, Republic of Korea. Electronic address: crane87@hanyang.ac.kr. ^[9]

主题词成年人(Adult);老年人(Aged);老年人, 80以上(Aged, 80 and over);动物(Animals);细胞分化(Cell Differentiation);细胞增殖(Cell Proliferation);细胞, 培养的(Cells, Cultured);女(雌)性(Female);糖原合成酶激酶3(Glycogen Synthase Kinase 3);肝细胞(Hepatocytes);人类(Humans);肝(Liver);肝再生(Liver Regeneration);男(雄)性(Male);小鼠(Mice);中年人(Middle Aged);模型, 动物(Models, Animal);吡唑类(Pyrazoles);吡啶类(Pyridines);嘧啶类(Pyrimidines);干细胞(Stem Cells);缩氨硫脲类(Thiosemicarbazones)

DOI 10.1016/j.jhep.2018.09.007

PMID 30240598

发布时间 2020-04-21

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Small molecule-mediated reprogramming of human hepatocytes into bipotent progenitor cells.

Journal of hepatology

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Journal of hepatology

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Small molecule-mediated reprogramming of human hepatocytes into bipotent progenitor cells.

Journal of hepatology

相似文献

Journal of hepatology

相关期刊

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