换一批
换一批Parenteral nanosuspensions: a brief review from solubility enhancement to more novel and specific applications.
作者：
关键词
ADME, absorption distribution metabolism eliminationASEs, aerosols solvent extractionsAUC, area under curveBBB, blood–brain barrierBCS, Biopharmaceutical Classification SystemBDP, beclomethasone dipropionateCFC, critical flocculation concentrationCLSM, confocal laser scanning microscopyCMC, critical micelle concentrationDMSO, dimethyl sulfoxideEDI, estimated daily intakeEHDA, electrohydrodynamic atomizationEPAS, evaporative precipitation in aqueous solutionEPR, enhanced permeability and retentionFITC, fluorescein isothiocyanateGRAS, Generally Recognized as SafeHEC, hydroxyethylcelluloseHFBII, class II hydrophobinHP-PTX/NC, hyaluronic acid-paclitaxel/nanocrystalHPC, hydroxypropyl celluloseHPH, high-pressure homogenizationHPMC, hydroxypropyl methylcelluloseIM, intramuscularIP, intraperitonealIV, intravenousIVIVC, in vivo–in vitro correlationIn vivo fateLD50, median lethal dose (50)MDR, multidrug resistance effectNCE, new chemical entitiesNanosuspensionP-gp, permeation glycoproteinPEG, polyethylene glycolPTX, paclitaxelPVA, polyvinyl alcoholParenteralQbD, quality by designSC, subcutaneousSEDS, solution enhanced dispersion by supercritical fluidsSEM, scanning electron microscopySFL, spray freezing into liquidsScalabilitySolidificationStabilizerTBA, tert-butanolTEM, transmission electron microscopyUS FDA, United States Food and Drug AdministrationVitamin E TPGS, d-α-tocopheryl polyethylene glycol 1000 succinate
DOI
10.1016/j.apsb.2018.07.011
PMID
30245962
发布时间
2023-09-28
- 浏览31
Acta pharmaceutica Sinica. B
2018年8卷5期
733-755页
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