Novel Hypoxia-Inducible Factor 1α (HIF-1α) Inhibitors for Angiogenesis-Related Ocular Diseases: Discovery of a Novel Scaffold via Ring-Truncation Strategy.

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作者： Hongchan,An ^[1] ; Seungbeom,Lee ^[1] ; Jung Min,Lee ^[1] ; Dong Hyun,Jo ^[2] ; Joohwan,Kim ^[3] ; Yoo-Seong,Jeong ^[1] ; Mi Jeong,Heo ^[1] ; Chang Sik,Cho ^[2] ; Hoon,Choi ^[1] ; Ji Hae,Seo ^[1] ; Seyeon,Hwang ^[1] ; Jihye,Lim ^[1] ; Taewoo,Kim ^[1] ; Hyoung Oh,Jun ^[2] ; Jaehoon,Sim ^[1] ; Changjin,Lim ^[4] ; Joonseong,Hur ^[1] ; Jungmin,Ahn ^[4] ; Hyun Su,Kim ^[1] ; Seung-Yong,Seo ^[1] ; Younghwa,Na ^[1] ; Seok-Ho,Kim ^[4] ; Jeewoo,Lee ^[5] ; Jeeyeon,Lee ^[4] ; Suk-Jae,Chung ^[4] ; Young-Myeong,Kim ^[1] ; Kyu-Won,Kim ^[1] ; Sang Geon,Kim ^[1] ; Jeong Hun,Kim ^[3] ; Young-Ger,Suh ^[1]

作者单位： College of Pharmacy , Seoul National University , Seoul 08826 , Republic of Korea. ^[1] Fight against Angiogenesis-Related Blindness (FARB) Laboratory, Clinical Research Institute , Seoul National University Hospital , Seoul 03080 , Republic of Korea. ^[2] Department of Molecular and Cellular Biochemistry, School of Medicine , Kangwon National University , Gangwon-do 24341 , Republic of Korea. ^[3] College of Pharmacy , CHA University , Gyeonggi-do 11160 , Republic of Korea. ^[4] College of Pharmacy , Gachon University , Incheon 21936 , Republic of Korea. ^[5] Department of Ophthalmology, College of Medicine , Seoul National University , Seoul 03080 , Republic of Korea. ^[6]