Powering the ABC multidrug exporter LmrA: How nucleotides embrace the ion-motive force.

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作者： Kelvin,Agboh ^[1] ; Calvin H F,Lau ^[1] ; Yvonne S K,Khoo ^[1] ; Himansha,Singh ^[1] ; Sagar,Raturi ^[1] ; Asha V,Nair ^[1] ; Julie,Howard ^[2] ; Marco,Chiapello ^[2] ; Renata,Feret ^[2] ; Michael J,Deery ^[2] ; Satoshi,Murakami ^[3] ; Hendrik W,van Veen ^[1]

作者单位： Department of Pharmacology, University of Cambridge, Tennis Court Road, Cambridge CB2 1PD, UK. ^[1] Cambridge Centre for Proteomics, University of Cambridge, Cambridge CB2 1GA, UK. ^[2] Department of Life Science and Technology, Tokyo Institute of Technology, Nagatsuta, Midori-ku, Yokohama 226-8501, Japan. ^[3]

主题词腺苷三磷酸(Adenosine Triphosphate);细菌蛋白质类(Bacterial Proteins);结合部位(Binding Sites);抗药性, 细菌(Drug Resistance, Bacterial);胡米胺(Ethidium);HEPES(HEPES);氢离子浓度(Hydrogen-Ion Concentration);乳杆菌属(Lactobacillus);脂双层(Lipid Bilayers);镁(Magnesium);多药耐药相关蛋白质类(Multidrug Resistance-Associated Proteins);膜片钳术(Patch-Clamp Techniques);磷脂类(Phospholipids);重组蛋白质类(Recombinant Proteins);钠(Sodium)

DOI 10.1126/sciadv.aas9365

PMID 30255140

发布时间 2022-01-29

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Science advances

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Powering the ABC multidrug exporter LmrA: How nucleotides embrace the ion-motive force.

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Powering the ABC multidrug exporter LmrA: How nucleotides embrace the ion-motive force.

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