Tumor-specific genetic variants can be detected in circulating cell-free DNA of malignant pleural mesothelioma patients.

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第一作者： Marieke,Hylebos

第一单位： Center of Medical Genetics, University of Antwerp and Antwerp University Hospital, Prins Boudewijnlaan 43, 2650 Antwerp, Belgium; Center for Oncological Research, University of Antwerp, Universiteitsplein 1, 2610 Antwerp, Belgium.

作者： Marieke,Hylebos ^[1] ; Ken,Op de Beeck ^[1] ; Patrick,Pauwels ^[2] ; Karen,Zwaenepoel ^[2] ; Jan P,van Meerbeeck ^[3] ; Guy,Van Camp ^[1]

作者单位： Center of Medical Genetics, University of Antwerp and Antwerp University Hospital, Prins Boudewijnlaan 43, 2650 Antwerp, Belgium; Center for Oncological Research, University of Antwerp, Universiteitsplein 1, 2610 Antwerp, Belgium. ^[1] Center for Oncological Research, University of Antwerp, Universiteitsplein 1, 2610 Antwerp, Belgium; Laboratory of Pathology, Antwerp University Hospital, Wilrijkstraat 10, 2650 Antwerp, Belgium. ^[2] Center for Oncological Research, University of Antwerp, Universiteitsplein 1, 2610 Antwerp, Belgium; Department of Pulmonology/Thoracic Oncology, Antwerp University Hospital, Wilrijkstraat 10, 2650 Antwerp, Belgium. Electronic address: Jan.VanMeerbeeck@uza.be. ^[3]

关键词 Circulating cell-free DNA Circulating cell-free tumor DNA Droplet digital PCR Malignant pleural mesothelioma Whole exome sequencing