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首页> Frontiers in immunology> The CBM-opathies-A Rapidly Expanding Spectrum of Human Inborn Errors of Immunity Caused by Mutations in the CARD11-BCL10-MALT1 Complex.

The CBM-opathies-A Rapidly Expanding Spectrum of Human Inborn Errors of Immunity Caused by Mutations in the CARD11-BCL10-MALT1 Complex.

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作者： Henry Y,Lu ^[1] ; Bradly M,Bauman ^[2] ; Swadhinya,Arjunaraja ^[3] ; Batsukh,Dorjbal ^[3] ; Joshua D,Milner ^[3] ; Andrew L,Snow ^[4] ; Stuart E,Turvey ^[3]

作者单位： Department of Pediatrics, British Columbia Children's Hospital, The University of British Columbia, Vancouver, BC, Canada. ^[1] Experimental Medicine Program, Faculty of Medicine, The University of British Columbia, Vancouver, BC, Canada. ^[2] Department of Pharmacology and Molecular Therapeutics, Uniformed Services University of the Health Sciences, Bethesda, MD, United States. ^[3] Laboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States. ^[4]

关键词 BCL10 BENTA CARD11 CBM complex MALT1 combined immunodeficiency primary atopic disease severe combined immunodeficiency

主题词 CARD信号接头蛋白质类(CARD Signaling Adaptor Proteins);鸟苷酸环化酶(Guanylate Cyclase);内环境稳定(Homeostasis);人类(Humans);淋巴细胞活化(Lymphocyte Activation);突变(Mutation);蛋白质结合(Protein Binding);重症联合免疫缺陷(Severe Combined Immunodeficiency);信号传导(Signal Transduction)

DOI 10.3389/fimmu.2018.02078

PMID 30283440

发布时间 2019-09-30

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