Fenofibrate improves vascular endothelial function and contractility in diabetic mice.

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第一作者： Nan,Xu

第一单位： Department of Physiology, School of Basic Medical Sciences, and Kidney Disease Center of First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310058, China.

作者： Nan,Xu ^[1] ; Qin,Wang ^[1] ; Shan,Jiang ^[1] ; Qijing,Wang ^[2] ; Weipeng,Hu ^[1] ; Suhan,Zhou ^[1] ; Liang,Zhao ^[1] ; Lanyu,Xie ^[3] ; Jianghua,Chen ^[1] ; Anton,Wellstein ^[4] ; En Yin,Lai ^[5]

作者单位： Department of Physiology, School of Basic Medical Sciences, and Kidney Disease Center of First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310058, China. ^[1] Department of Reproductive Endocrinology, Women's Hospital, Zhejiang University School of Medicine, Hangzhou 310058, China. ^[2] Medical college, Nanchang University, Nanchang 330000, China. ^[3] Lombardi Cancer Center, Georgetown University, Washington, DC 20007, USA. ^[4] Department of Physiology, School of Basic Medical Sciences, and Kidney Disease Center of First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310058, China. Electronic address: laienyin@zju.edu.cn. ^[5]

关键词 Diabetes Endothelial dysfunction Fenofibrate Nitric oxide Oxidative stress

主题词动物(Animals);环氧化酶2(Cyclooxygenase 2);糖尿病, 实验性(Diabetes Mellitus, Experimental);内皮, 血管(Endothelium, Vascular);非诺贝特(Fenofibrate);过氧化氢(Hydrogen Peroxide);降血脂药物(Hypolipidemic Agents);肾(Kidney);脂类(Lipids);男(雄)性(Male);小鼠(Mice);微血管(Microvessels);模型, 生物学(Models, Biological);NF-κB(NF-kappa B);一氧化氮(Nitric Oxide);一氧化氮合酶Ⅲ型(Nitric Oxide Synthase Type III);氧化性应激(Oxidative Stress);过氧化物酶体增殖物激活受体(Peroxisome Proliferator-Activated Receptors)

DOI 10.1016/j.redox.2018.09.024

PMID 30296701

发布时间 2019-04-01

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Redox biology

2019年20卷

87-97页

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Fenofibrate improves vascular endothelial function and contractility in diabetic mice.

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Fenofibrate improves vascular endothelial function and contractility in diabetic mice.

Redox biology

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Redox biology

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