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首页> Journal of pharmaceutical and biomedical analysis> Qualitative and quantitative analysis of Yifei Tongluo granules to identify main bioactive components using LC-DAD/MS and pharmacokinetic studies.

Qualitative and quantitative analysis of Yifei Tongluo granules to identify main bioactive components using LC-DAD/MS and pharmacokinetic studies.

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作者： Yongjie,Wang ^[1] ; Bin,Zhang ^[1] ; Jiaozhen,Zhang ^[2] ; Xiaona,Tian ^[1] ; Deqing,Sun ^[1] ; Qiang,Li ^[3] ; Rongmei,Wang ^[4]

作者单位： Department of Pharmacy, The Second Hospital of Shandong University, Shandong University, Jinan, Shandong 250033, PR China. ^[1] Department of Natural Products Chemistry, Key Lab of Chemical Biology of Ministry of Education, Shandong University, Jinan, Shandong 250012, PR China. ^[2] Department of Pharmacy, The Second Hospital of Shandong University, Shandong University, Jinan, Shandong 250033, PR China. Electronic address: 2837976216@qq.com. ^[3] Department of Pharmacy, The Second Hospital of Shandong University, Shandong University, Jinan, Shandong 250033, PR China. Electronic address: rongmeiwang@hotmail.com. ^[4]

关键词 LC–MS/MS Militarine Pharmacokinetic Quantitative method Yifei Tongluo granules

主题词动物(Animals);化学分馏法(Chemical Fractionation);色谱法, 高压液相(Chromatography, High Pressure Liquid);药物调剂(Drug Compounding);药物相互作用(Drug Interactions);中草药(Drugs, Chinese Herbal);男(雄)性(Male);质量控制(Quality Control);大鼠(Rats);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);结果可重复性(Reproducibility of Results);光谱法, 质量, 电喷雾电离(Spectrometry, Mass, Electrospray Ionization);琥珀酸盐(Succinates);串联质谱法(Tandem Mass Spectrometry)

DOI 10.1016/j.jpba.2018.09.017

PMID 30296714

发布时间 2019-12-10

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Journal of pharmaceutical and biomedical analysis

130-136页

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