Her2-Targeted Therapy Induces Autophagy in Esophageal Adenocarcinoma Cells.

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作者： Félice A,Janser ^[1] ; Olivia,Adams ^[2] ; Vanessa,Bütler ^[3] ; Anna M,Schläfli ^[4] ; Bastian,Dislich ^[5] ; Christian A,Seiler ^[6] ; Dino,Kröll ^[7] ; Rupert,Langer ^[8] ; Mario P,Tschan ^[9]

作者单位： Institute of Pathology, University of Bern, Murtenstrasse 31, 3008 Bern, Switzerland. ariane.janser@pathology.unibe.ch. ^[1] Graduate School for Cellular and Biomedical Sciences, University of Bern, Freiestr. 1, 3012 Bern, Switzerland. ariane.janser@pathology.unibe.ch. ^[2] Institute of Pathology, University of Bern, Murtenstrasse 31, 3008 Bern, Switzerland. olivia.adams@pki.unibe.ch. ^[3] Graduate School for Cellular and Biomedical Sciences, University of Bern, Freiestr. 1, 3012 Bern, Switzerland. olivia.adams@pki.unibe.ch. ^[4] Institute of Pathology, University of Bern, Murtenstrasse 31, 3008 Bern, Switzerland. vanessa.buetler@students.unibe.ch. ^[5] Institute of Pathology, University of Bern, Murtenstrasse 31, 3008 Bern, Switzerland. anna.schlaefli@pathology.unibe.ch. ^[6] Institute of Pathology, University of Bern, Murtenstrasse 31, 3008 Bern, Switzerland. bastian.dislich@pathology.unibe.ch. ^[7] Department of Visceral Surgery and Medicine, University Hospital Bern, 3010 Bern, Switzerland. christian.a.seiler@insel.ch. ^[8] Department of Visceral Surgery and Medicine, University Hospital Bern, 3010 Bern, Switzerland. dino.kroell@insel.ch. ^[9] Institute of Pathology, University of Bern, Murtenstrasse 31, 3008 Bern, Switzerland. rupert.langer@pathology.unibe.ch. ^[10] Institute of Pathology, University of Bern, Murtenstrasse 31, 3008 Bern, Switzerland. mario.tschan@pathology.unibe.ch. ^[11] Graduate School for Cellular and Biomedical Sciences, University of Bern, Freiestr. 1, 3012 Bern, Switzerland. mario.tschan@pathology.unibe.ch. ^[12]

关键词 Her2 Her2 inhibitor LC3B Lapatinib OE19 autophagy esophageal adenocarcinoma p62 resistance