Distinct virulence ranges for infection of mice by Bordetella pertussis revealed by engineering of the sensor-kinase BvgS.
作者:
主题词
动物(Animals);细菌蛋白质类(Bacterial Proteins);百日咳博德特菌(Bordetella pertussis);疾病模型, 动物(Disease Models, Animal);基因表达谱(Gene Expression Profiling);基因表达调控, 细菌(Gene Expression Regulation, Bacterial);宿主与病原体相互作用(Host-Pathogen Interactions);肺(Lung);小鼠(Mice);突变(Mutation);鼻(Nose);蛋白质工程(Protein Engineering);序列分析, RNA(Sequence Analysis, RNA);转录因子(Transcription Factors);毒力(Virulence);百日咳(Whooping Cough)
DOI
10.1371/journal.pone.0204861
PMID
30307950
发布时间
2019-03-22
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PloS one
e0204861页
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