Integrating omics datasets with the OmicsPLS package.

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作者： Said El,Bouhaddani ^[1] ; Hae-Won,Uh ^[2] ; Geurt,Jongbloed ^[3] ; Caroline,Hayward ^[4] ; Lucija,Klarić ^[5] ; Szymon M,Kiełbasa ^[6] ; Jeanine,Houwing-Duistermaat ^[5]

作者单位： Dept. of Biomedical Data Sciences, LUMC, Albinusdreef 2, Leiden, 2300 RC, The Netherlands. s.el_bouhaddani@lumc.nl. ^[1] Delft Institute of Applied Mathematics, EEMCS, TU Delft, Van Mourik Broekmanweg 6, Delft, 2628 XE, The Netherlands. s.el_bouhaddani@lumc.nl. ^[2] Department of Biostatistics and Research Support, UMC Utrecht, div. Julius Centre, Huispost Str. 6.131, Utrecht, 3508 GA, The Netherlands. ^[3] Delft Institute of Applied Mathematics, EEMCS, TU Delft, Van Mourik Broekmanweg 6, Delft, 2628 XE, The Netherlands. ^[4] MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, EH4 2XU, Scotland. ^[5] Genos Glycobiology Laboratory, Zagreb, 10000, Croatia. ^[6] Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, EH8 9DX, Scotland. ^[7] Dept. of Biomedical Data Sciences, LUMC, Albinusdreef 2, Leiden, 2300 RC, The Netherlands. ^[8] Dept. of Statistics, University of Leeds, Leeds, LS2 9JT, United Kingdom. ^[9]

关键词 Data-specific variation Joint principal components O2PLS Omics data integration R package

主题词基因组学(Genomics);人类(Humans);最小二乘法分析(Least-Squares Analysis);代谢组学(Metabolomics);软件(Software)

DOI 10.1186/s12859-018-2371-3

PMID 30309317

发布时间 2024-03-06

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