Chromatin mapping identifies BasR, a key regulator of bacteria-triggered production of fungal secondary metabolites.

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作者： Juliane,Fischer ^[1] ; Sebastian Y,Müller ^[2] ; Tina,Netzker ^[3] ; Nils,Jäger ^[1] ; Agnieszka,Gacek-Matthews ^[4] ; Kirstin,Scherlach ^[5] ; Maria C,Stroe ^[6] ; María,García-Altares ^[7] ; Francesco,Pezzini ^[1] ; Hanno,Schoeler ^[2] ; Michael,Reichelt ^[7] ; Jonathan,Gershenzon ^[3] ; Mario Kc,Krespach ^[1] ; Ekaterina,Shelest ^[2] ; Volker,Schroeckh ^[8] ; Vito,Valiante ^[8] ; Thorsten,Heinzel ^[1] ; Christian,Hertweck ^[2] ; Joseph,Strauss ^[3] ; Axel A,Brakhage ^[1]

作者单位： Department of Molecular and Applied Microbiology, Leibniz Institute for Natural Product Research and Infection Biology, Jena, Germany. ^[1] Institute of Microbiology, Friedrich Schiller University Jena, Jena, Germany. ^[2] Systems Biology and Bioinformatics, Leibniz Institute for Natural Product Research and Infection Biology, Jena, Germany. ^[3] Department of Biochemistry, Friedrich Schiller University, Jena, Germany. ^[4] Department for Applied Genetics and Cell Biology, BOKU University of Natural Resources and Life Sciences, Vienna, Austria. ^[5] Institute of Microbiology, University of Veterinary Medicine, Vienna, Austria. ^[6] Department of Biomolecular Chemistry, Leibniz Institute for Natural Product Research and Infection Biology, Jena, Germany. ^[7] Department of Biochemistry, Max Planck Institute for Chemical Ecology, Jena, Germany. ^[8] Leibniz Research Group - Biobricks of Microbial Natural Product Syntheses, Leibniz Institute for Natural Product Research and Infection Biology, Jena, Germany. ^[9] Chair for Natural Product Chemistry, Friedrich Schiller University, Jena, Germany. ^[10]

关键词 Aspergillus nidulans genome-wide dual ChIP-seq histone modification infectious disease microbial interaction microbiology secondary metabolism transcription factors