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LILRB4 signalling in leukaemia cells mediates T cell suppression and tumour infiltration.

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作者: Mi,Deng [1] ; Xun,Gui [2] ; Jaehyup,Kim [3] ; Li,Xie [4] ; Weina,Chen [3] ; Zunling,Li [1] ; Licai,He [5] ; Yuanzhi,Chen [1] ; Heyu,Chen [6] ; Weiguang,Luo [2] ; Zhigang,Lu [7] ; Jingjing,Xie [1] ; Hywyn,Churchill [1] ; Yixiang,Xu [8] ; Zhan,Zhou [1] ; Guojin,Wu [9] ; Chenyi,Yu [1] ; Samuel,John [5] ; Kouyuki,Hirayasu [3] ; Nam,Nguyen [2] ; Xiaoye,Liu [1] ; Fangfang,Huang [1] ; Leike,Li [2] ; Hui,Deng [10] ; Haidong,Tang [11] ; Ali H,Sadek [12] ; Lingbo,Zhang [1] ; Tao,Huang [1] ; Yizhou,Zou [1] ; Benjamin,Chen [13] ; Hong,Zhu [2] ; Hisashi,Arase [2] ; Ningshao,Xia [3] ; Youxing,Jiang [1] ; Robert,Collins [1] ; M James,You [10] ; Jade,Homsi [14] ; Nisha,Unni [8] ; Cheryl,Lewis [15] ; Guo-Qiang,Chen [16] ; Yang-Xin,Fu [17] ; X Charlene,Liao [12] ; Zhiqiang,An [7] ; Junke,Zheng [1] ; Ningyan,Zhang [18] ; Cheng Cheng,Zhang [19]
作者单位: Department of Physiology, University of Texas Southwestern Medical Center, Dallas, TX, USA. [1] Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, McGovern Medical School, University of Texas Health Science Center, Houston, TX, USA. [2] Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX, USA. [3] Department of Pathophysiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai Jiao Tong University School of Medicine, Shanghai, China. [4] Taishan Immunology Program, Basic Medicine School, Binzhou Medical University, Yantai, China. [5] Key Laboratory of Laboratory Medicine, Ministry of Education, School of Laboratory Medical and Life Science, Wenzhou Medical University, Wenzhou, China. [6] School of Public Health, Xiamen University, Xiamen, China. [7] Department of Immunology, Xiangya Medical School, Central South University, Changsha, China. [8] Institute of Biomedical Sciences and the Fifth People's Hospital of Shanghai, Fudan University, Shanghai, China. [9] Xiangya Medical School, Central South University, Changsha, China. [10] Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA. [11] Department of Immunochemistry, Research Institute for Microbial Diseases and Laboratory of Immunochemistry, World Premier International Immunology Frontier Research Center, Osaka University, Osaka, Japan. [12] Department of Hematology, Zhongshan Hospital, Xiamen University, Xiamen, China. [13] Immune-Onc Therapeutics, Inc., Palo Alto, CA, USA. [14] Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX, USA. [15] Department of Clinical Sciences, University of Texas Southwestern Medical Center, Dallas, TX, USA. [16] Harold C. Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX, USA. [17] Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA. [18] Department of Hematopathology, Division of Pathology and Laboratory Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. [19] Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, McGovern Medical School, University of Texas Health Science Center, Houston, TX, USA. zhiqiang.an@uth.tmc.edu. [20] Department of Pathophysiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai Jiao Tong University School of Medicine, Shanghai, China. zhengjunke@sjtu.edu.cn. [21] Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, McGovern Medical School, University of Texas Health Science Center, Houston, TX, USA. ningyan.zhang@uth.tmc.edu. [22] Department of Physiology, University of Texas Southwestern Medical Center, Dallas, TX, USA. alec.zhang@utsouthwestern.edu. [23]
DOI 10.1038/s41586-018-0615-z
PMID 30333625
发布时间 2024-06-10
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