Cellulose nanocrystal cationic derivative induces NLRP3 inflammasome-dependent IL-1β secretion associated with mitochondrial ROS production.
作者:
关键词
AEM, aminoethylmethacrylateAEMA, aminoethylmethacrylamideASC, apoptosis-associated speck-like protein containing a CARDCNCs, cellulose nanocrystalsCationic needle-like nanomaterialCellulose nanocrystalsDAMPS, danger-associated molecular pattern moleculesDSL, Dynamic light scatteringELISA, enzyme-linked immuno assayH2DCF-DA, 2′, 7′-dichlorodihydrofluorescein diacetateHRP, horseradish peroxidase-conjugatedHTCFNWs, high-temperature calcined fullerene nanowhiskersIL-1βIL-1β, Interleukin 1βJC-1, 5,5′,6,6′-tetrachloro-1,1′,3,3′-tetraethylbenzimidazol-carbocyanine iodideLPS, lipopolysaccharideMWCNTs, needle-like multi-wall carbon nanotubesMitochondrial ROSMouse macrophagesNLRP3 inflammasomeNLRP3, NOD-like receptor, pyrin domain-containing 3PAMPs, pathogen-associated molecular pattern moleculesPBMCs, peripheral blood mononuclear cellsROS, reactive oxygen speciesSAA, serum amyloid ASDS-PAGE, sodium dodecyl sulfate polyacrylamide gelTMB, 3,3′,5,5′ tetramethylbezidine
DOI
10.1016/j.bbrep.2015.08.008
PMID
30338301
发布时间
2020-09-29
- 浏览4
Biochemistry and biophysics reports
2015年4卷
1-9页
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