Effect of Protocolized Weaning With Early Extubation to Noninvasive Ventilation vs Invasive Weaning on Time to Liberation From Mechanical Ventilation Among Patients With Respiratory Failure: The Breathe Randomized Clinical Trial.

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作者： Gavin D,Perkins ^[1] ; Dipesh,Mistry ^[2] ; Simon,Gates ^[1] ; Fang,Gao ^[1] ; Catherine,Snelson ^[3] ; Nicholas,Hart ^[2] ; Luigi,Camporota ^[3] ; James,Varley ^[4] ; Coralie,Carle ^[5] ; Elankumaran,Paramasivam ^[5] ; Beverley,Hoddell ^[6] ; Daniel F,McAuley ^[7] ; Timothy S,Walsh ^[8] ; Bronagh,Blackwood ^[1] ; Louise,Rose ^[9] ; Sarah E,Lamb ^[10] ; Stavros,Petrou ^[9] ; Duncan,Young ^[11] ; Ranjit,Lall ^[12] ; Breathe Collaborators ^[13]

作者单位： Warwick Clinical Trials Unit, University of Warwick, Coventry, England. ^[1] Heartlands Hospital, University Hospitals Birmingham NHS Foundation Trust, Birmingham, England. ^[2] Cancer Research United Kingdom Clinical Trials Unit, University of Birmingham, Birmingham, England. ^[3] Queen Elizabeth Hospital, University Hospitals Birmingham NHS Foundation Trust, Birmingham, England. ^[4] Guy's and St Thomas' NHS Foundation Trust, London, England. ^[5] Addenbrooke's Hospital, Cambridge, England. ^[6] Peterborough and Stamford Hospitals NHS Foundation Trust, Peterborough, England. ^[7] Leeds Teaching Hospitals, Leeds, England. ^[8] Queen's University of Belfast, Belfast, Northern Ireland. ^[9] University of Edinburgh, Edinburgh, Scotland. ^[10] University of Toronto, Toronto, Ontario, Canada. ^[11] Kings College London, London, England. ^[12] University of Oxford, Oxford, England. ^[13]