换一批
换一批Deep multi-region whole-genome sequencing reveals heterogeneity and gene-by-environment interactions in treatment-naive, metastatic lung cancer.
作者：
Tracy L,Leong [1]
;
Velimir,Gayevskiy [2]
;
Daniel P,Steinfort [3]
;
Marc R,De Massy [2]
;
Alvaro,Gonzalez-Rajal [4]
;
Kieren D,Marini [5]
;
Emily,Stone [6]
;
Venessa,Chin [7]
;
Adrian,Havryk [8]
;
Marshall,Plit [8]
;
Louis B,Irving [3]
;
Barton R,Jennings [9]
;
Rachael A,McCloy [4]
;
W Samantha N,Jayasekara [5]
;
Muhammad,Alamgeer [5]
;
Vishal,Boolell [5]
;
Andrew,Field [10]
;
Prudence A,Russell [11]
;
Beena,Kumar [12]
;
Daniel J,Gough [13]
;
Anette,Szczepny [5]
;
Vinod,Ganju [13]
;
Fernando J,Rossello [14]
;
Jason E,Cain [13]
;
Anthony T,Papenfuss [15]
;
Marie-Liesse,Asselin-Labat [16]
;
Mark J,Cowley [17]
;
D Neil,Watkins [18]
作者单位：
ACRF Stem Cells and Cancer Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3050, Australia.;Department of Medical Biology, University of Melbourne, Parkville, VIC, 3050, Australia.
[1]
The Kinghorn Centre for Clinical Genomics, Garvan Institute of Medical Research, Darlinghurst, NSW, 2010, Australia.
[2]
Department of Medical Biology, University of Melbourne, Parkville, VIC, 3050, Australia.;Department of Respiratory Medicine, Royal Melbourne Hospital, Parkville, VIC, 3050, Australia.
[3]
The Kinghorn Cancer Centre, Garvan Institute of Medical Research, Darlinghurst, NSW, 2010, Australia.
[4]
The Hudson Institute of Medical Research, Clayton, VIC, 3168, Australia.
[5]
The Hudson Institute of Medical Research, Clayton, VIC, 3168, Australia.;Department of Thoracic Medicine, St Vincent's Hospital, Darlinghurst, NSW, 2010, Australia.
[6]
The Kinghorn Cancer Centre, Garvan Institute of Medical Research, Darlinghurst, NSW, 2010, Australia.;St Vincent's Clinical School, UNSW Sydney, Darlinghurst, NSW, 2010, Australia.;Department of Medical Oncology, St Vincent's Hospital, Darlinghurst, NSW, 2010, Australia.
[7]
Department of Thoracic Medicine, St Vincent's Hospital, Darlinghurst, NSW, 2010, Australia.;St Vincent's Clinical School, UNSW Sydney, Darlinghurst, NSW, 2010, Australia.
[8]
Department of Respiratory and Sleep Medicine, Monash Health, Clayton, VIC, 3168, Australia.
[9]
St Vincent's Clinical School, UNSW Sydney, Darlinghurst, NSW, 2010, Australia.;Department of Pathology, St Vincent's Hospital, Sydney, NSW, 2010, Australia.
[10]
Department of Pathology, St Vincent's Hospital Melbourne, Fitzroy, VIC, 3000, Australia.
[11]
Department of Pathology, Monash Health, Clayton, VIC, 3168, Australia.
[12]
The Hudson Institute of Medical Research, Clayton, VIC, 3168, Australia.;Department of Molecular and Translational Science, Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, VIC, Australia.
[13]
Department of Anatomy and Developmental Biology, Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, VIC, 3168, Australia.;Australian Regenerative Medicine Institute, Monash University, Clayton, VIC, 3168, Australia.
[14]
Computational Cancer Biology Program, Peter MacCallum Cancer Centre, Melbourne, VIC, 3000, Australia.;Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, VIC, 3052, Australia.;Bioinformatics Division, The Walter & Eliza Hall Institute of Medical Research, Parkville, VIC, 3052, Australia.
[15]
ACRF Stem Cells and Cancer Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, 3050, Australia. labat@wehi.edu.au.;Department of Medical Biology, University of Melbourne, Parkville, VIC, 3050, Australia. labat@wehi.edu.au.
[16]
The Kinghorn Centre for Clinical Genomics, Garvan Institute of Medical Research, Darlinghurst, NSW, 2010, Australia. m.cowley@garvan.org.au.;St Vincent's Clinical School, UNSW Sydney, Darlinghurst, NSW, 2010, Australia. m.cowley@garvan.org.au.;Children's Cancer Institute, Kensington, NSW, 2750, Australia. m.cowley@garvan.org.au.
[17]
The Kinghorn Cancer Centre, Garvan Institute of Medical Research, Darlinghurst, NSW, 2010, Australia. dr.neil.watkins@gmail.com.;Department of Thoracic Medicine, St Vincent's Hospital, Darlinghurst, NSW, 2010, Australia. dr.neil.watkins@gmail.com.;St Vincent's Clinical School, UNSW Sydney, Darlinghurst, NSW, 2010, Australia. dr.neil.watkins@gmail.com.;Department of Medical Oncology, St Vincent's Hospital, Darlinghurst, NSW, 2010, Australia. dr.neil.watkins@gmail.com.
[18]
主题词
老年人(Aged);老年人, 80以上(Aged, 80 and over);癌, 鳞状细胞(Carcinoma, Squamous Cell);DNA拷贝数变异(DNA Copy Number Variations);女(雌)性(Female);建立者效应(Founder Effect);遗传异质性(Genetic Heterogeneity);高通量核苷酸序列分析(High-Throughput Nucleotide Sequencing);人类(Humans);肺肿瘤(Lung Neoplasms);男(雄)性(Male);中年人(Middle Aged);突变(Mutation);小细胞肺癌(Small Cell Lung Carcinoma);胸部肿瘤(Thoracic Neoplasms);肿瘤微环境(Tumor Microenvironment)
DOI
10.1038/s41388-018-0536-1
PMID
30348992
发布时间
2024-07-19
- 浏览6
Oncogene
Oncogene
1661-1675页
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