首页> International journal of nanomedicine> Involvement of complement activation in the pulmonary vasoactivity of polystyrene nanoparticles in pigs: unique surface properties underlying alternative pathway activation and instant opsonization.

Involvement of complement activation in the pulmonary vasoactivity of polystyrene nanoparticles in pigs: unique surface properties underlying alternative pathway activation and instant opsonization.

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第一作者： Tamás,Mészáros

第一单位： Nanomedicine Research and Education Center, Department of Pathophysiology, Semmelweis University, Budapest, Hungary, jszebeni2@gmail.com.;SeroScience Ltd, Budapest, Hungary, jszebeni2@gmail.com.

作者： Tamás,Mészáros ^[1] ; Gergely Tibor,Kozma ^[2] ; Taro,Shimizu ^[3] ; Koga,Miyahara ^[3] ; Keren,Turjeman ^[4] ; Tatsuhiro,Ishida ^[3] ; Yechezkel,Barenholz ^[4] ; Rudolf,Urbanics ^[1] ; János,Szebeni ^[5]

作者单位： Nanomedicine Research and Education Center, Department of Pathophysiology, Semmelweis University, Budapest, Hungary, jszebeni2@gmail.com.;SeroScience Ltd, Budapest, Hungary, jszebeni2@gmail.com. ^[1] SeroScience Ltd, Budapest, Hungary, jszebeni2@gmail.com. ^[2] Department of Pharmacokinetics and Biopharmaceutics, Institute of Biomedical Sciences, Tokushima University, Tokushima, Japan. ^[3] Laboratory of Membrane and Liposome Research, Department of Biochemistry and Molecular Biology, Institute for Medical Research Israel-Canada (IMRIC), The Hebrew University-Hadassah Medical School, Jerusalem, Israel. ^[4] Nanomedicine Research and Education Center, Department of Pathophysiology, Semmelweis University, Budapest, Hungary, jszebeni2@gmail.com.;SeroScience Ltd, Budapest, Hungary, jszebeni2@gmail.com.;Department of Nanobiotechnology and Regenerative Medicine, Faculty of Health, Miskolc University, Miskolc, Hungary, jszebeni2@gmail.com. ^[5]

关键词 PIM cells adverse drug reactions anaphyla-toxins immunotoxicity nanoparticles phagocytosis pseudoallergy