Improving hematopoietic recovery through modeling and modulation of the mesenchymal stromal cell secretome.

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作者： Frances D,Liu ^[1] ; Kimberley,Tam ^[2] ; Novalia,Pishesha ^[2] ; Zhiyong,Poon ^[1] ; Krystyn J,Van Vliet ^[3]

作者单位： Department of Biological Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, 02139, USA. ^[1] Biosystems and Micromechanics (BioSyM) Interdisciplinary Research Group, Singapore-MIT Alliance for Research and Technology, 1 Create Way, Singapore, 138602, Singapore. ^[2] Whitehead Institute for Biomedical Research, 455 Main Street, Cambridge, MA, 02139, USA. ^[3] Department of Biological Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, 02139, USA. krystyn@mit.edu. ^[4] Biosystems and Micromechanics (BioSyM) Interdisciplinary Research Group, Singapore-MIT Alliance for Research and Technology, 1 Create Way, Singapore, 138602, Singapore. krystyn@mit.edu. ^[5] Department of Materials Science and Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, 02139, USA. krystyn@mit.edu. ^[6]

关键词 Hematopoietic recovery Mechanobiology Mesenchymal stromal cells Radiation injury Secretome