Melatonin protects vertebral endplate chondrocytes against apoptosis and calcification via the Sirt1-autophagy pathway.

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第一作者： Zengjie,Zhang

第一单位： Department of Orthopaedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, China.

作者： Zengjie,Zhang ^[1] ; Jialiang,Lin ^[2] ; Naifeng,Tian ^[3] ; Yaosen,Wu ^[1] ; Yifei,Zhou ^[2] ; Chenggui,Wang ^[3] ; Qingqing,Wang ^[1] ; Haiming,Jin ^[2] ; Tingting,Chen ^[3] ; Majid,Nisar ^[1] ; Gang,Zheng ^[2] ; Tianzhen,Xu ^[3] ; Weiyang,Gao ^[1] ; Xiaolei,Zhang ^[2] ; Xiangyang,Wang ^[3]

作者单位： Department of Orthopaedics, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, China. ^[1] Zhejiang Provincial Key Laboratory of Orthopaedics, Wenzhou, Zhejiang Province, China. ^[2] The Second School of Medicine, Wenzhou Medical University, Wenzhou, Zhejiang Province, China. ^[3] The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang Province, China. ^[4] The Third Affiliated Hospital and Ruian People's Hospital of Wenzhou Medical University, Ruian, Zhejiang Province, China. ^[5] Chinese Orthopaedic Regenerative Medicine Society, Zhejiang University of School Medicne, HangZhou, China. ^[6]

关键词 apoptosis autophagy calcification intervertebral disc degeneration melatonin vertebral endplate chondrocytes