Transcriptional Heterogeneity of <i>Cryptococcus gattii</i> VGII Compared with Non-VGII Lineages Underpins Key Pathogenicity Pathways.

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第一作者： Rhys A,Farrer

第一单位： MRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, School of Public Health, Imperial College London, London, United Kingdom rfarrer@broadinstitute.org.

作者： Rhys A,Farrer ^[1] ; Christopher B,Ford ^[2] ; Johanna,Rhodes ^[3] ; Toni,Delorey ^[2] ; Robin C,May ^[4] ; Matthew C,Fisher ^[2] ; Elaine,Cloutman-Green ^[5] ; Francois,Balloux ^[4] ; Christina A,Cuomo ^[6]

作者单位： MRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, School of Public Health, Imperial College London, London, United Kingdom rfarrer@broadinstitute.org. ^[1] Infectious Disease and Microbiome Program, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA. ^[2] UCL Genetics Institute, University College London, London, United Kingdom. ^[3] MRC Centre for Global Infectious Disease Analysis, Department of Infectious Disease Epidemiology, School of Public Health, Imperial College London, London, United Kingdom. ^[4] Institute of Microbiology and Infection & School of Biosciences, University of Birmingham, Birmingham, United Kingdom. ^[5] Department of Microbiology, Virology & Infection Prevention & Control, Great Ormond Street Hospital NHS Foundation Trust, London, United Kingdom. ^[6]

关键词 Cryptococcus capsule ergosterol host response host-pathogen interactions laccase mRNA

主题词动物(Animals);隐球菌病(Cryptococcosis);格特隐球菌(Cryptococcus gattii);基因表达调控, 真菌(Gene Expression Regulation, Fungal);基因, 交配型, 真菌(Genes, Mating Type, Fungal);小鼠(Mice);转录, 遗传(Transcription, Genetic);毒力(Virulence)

DOI 10.1128/mSphere.00445-18

PMID 30355668

发布时间 2022-05-18

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Transcriptional Heterogeneity of <i>Cryptococcus gattii</i> VGII Compared with Non-VGII Lineages Underpins Key Pathogenicity Pathways.

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Transcriptional Heterogeneity of <i>Cryptococcus gattii</i> VGII Compared with Non-VGII Lineages Underpins Key Pathogenicity Pathways.

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