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Effect of Human Recombinant Alkaline Phosphatase on 7-Day Creatinine Clearance in Patients With Sepsis-Associated Acute Kidney Injury: A Randomized Clinical Trial.

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第一作者: Peter,Pickkers
第一单位: Department of Intensive Care Medicine, Radboud University Nijmegen Medical Center, Nijmegen, the Netherlands.
作者单位: Department of Intensive Care Medicine, Radboud University Nijmegen Medical Center, Nijmegen, the Netherlands. [1] Department of Medicine, University of California, San Diego, Medical Center. [2] School of Medicine, University College Dublin, Dublin, Ireland. [3] Department of Internal Medicine, Division of Intensive Care and Emergency Medicine, Medical University Innsbruck, Innsbruck, Austria. [4] Indiana University, Indianapolis. [5] Department of Critical Care Medicine, Center for Critical Care Nephrology, University of Pittsburgh, Pittsburgh, Pennsylvania. [6] Department of General and Surgical Critical Care Medicine, Medical University Innsbruck, Innsbruck, Austria. [7] Intensive Care, Ghent University, Ghent, Belgium.;Clinical Research Foundation Flanders, Brussels, Belgium. [8] Intensive Care, Canisius Wilhelmina Hospital, Nijmegen, the Netherlands. [9] Internal Medicine, Eastern Idaho Regional Medical Center, Idaho Falls. [10] Guy's and St Thomas' Hospital, King's College London, London, United Kingdom. [11] Intensive Care, Jeroen Bosch Hospital, 's-Hertogenbosch, the Netherlands. [12] Division of Anesthesia and Intensive Care Medicine, Helsinki University Central Hospital, Helsinki, Finland. [13] Division of Critical Care, University College London Hospitals National Institute for Health Research Biomedical Research Centre, London, United Kingdom.;Bloomsbury Institute of Intensive Care Medicine, University College Hospital, London, United Kingdom. [14] Intensive Care, Medisch Spectrum Twente, Enschede, the Netherlands. [15] Faculté de Médecine, Service de Réanimation, Université de Strasbourg, Hôpitaux Universitaires de Strasbourg, Nouvel Hôpital Civil, Strasbourg, France. [16] Department of Critical Care Medicine, Center for Critical Care Nephrology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania. [17] Department of Intensive Care, Erasmus Medical Centre, Rotterdam, the Netherlands. [18] Unité Mixte de Recherche INSERM 1160, University Paris 7 Denis Diderot, Paris, France.;Department of Anaesthesiology and Critical Care, Hôpital Lariboisière, Assistance Publique-Hôpitaux de Paris, Paris, France. [19] Clinical Department, AM-Pharma BV, Bunnik, the Netherlands. [20]
DOI 10.1001/jama.2018.14283
PMID 30357272
发布时间 2019-10-29
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