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Nivolumab plus ipilimumab or nivolumab alone versus ipilimumab alone in advanced melanoma (CheckMate 067): 4-year outcomes of a multicentre, randomised, phase 3 trial.

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第一作者： Frank Stephen,Hodi

第一单位： Dana-Farber Cancer Institute, Boston, MA, USA. Electronic address: stephen_hodi@dfci.harvard.edu.

作者： Frank Stephen,Hodi ^[1] ; Vanna,Chiarion-Sileni ^[2] ; Rene,Gonzalez ^[3] ; Jean-Jacques,Grob ^[4] ; Piotr,Rutkowski ^[5] ; Charles Lance,Cowey ^[6] ; Christopher D,Lao ^[7] ; Dirk,Schadendorf ^[8] ; John,Wagstaff ^[9] ; Reinhard,Dummer ^[10] ; Pier Francesco,Ferrucci ^[11] ; Michael,Smylie ^[12] ; Andrew,Hill ^[13] ; David,Hogg ^[14] ; Ivan,Marquez-Rodas ^[15] ; Joel,Jiang ^[16] ; Jasmine,Rizzo ^[16] ; James,Larkin ^[17] ; Jedd D,Wolchok ^[18]

作者单位： Dana-Farber Cancer Institute, Boston, MA, USA. Electronic address: stephen_hodi@dfci.harvard.edu. ^[1] Veneto Institute of Oncology IOV-IRCCS, Padua, Italy. ^[2] University of Colorado Cancer Center, Denver, CO, USA. ^[3] Aix-Marseille University and APHM Hospital CHU Timone, Marseille, France. ^[4] Maria Skłodowska-Curie Institute - Oncology Centre, Warsaw, Poland. ^[5] Texas Oncology-Baylor Charles A Sammons Cancer Center, Dallas, TX, USA. ^[6] Department of Oncology, University of Michigan, Ann Arbor, MI, USA. ^[7] Department of Dermatology, University of Essen, Essen, Germany; German Cancer Consortium, Heidelberg, Germany. ^[8] The College of Medicine, Swansea University, Swansea, UK. ^[9] Department of Dermatology, Universitäts Spital, Zürich, Switzerland. ^[10] European Institute of Oncology, Milan, Italy. ^[11] Cross Cancer Institute, Edmonton, AB, Canada. ^[12] Tasman Oncology Research, Southport, QLD, Australia. ^[13] Princess Margaret Cancer Centre, Toronto, ON, Canada. ^[14] General University Hospital Gregorio Marañón, Madrid, Spain. ^[15] Bristol-Myers Squibb, Princeton, NJ, USA. ^[16] The Royal Marsden NHS Foundation Trust, London, UK. ^[17] Memorial Sloan Kettering Cancer Center, New York, NY, USA; Weill Cornell Medical College, New York, NY, USA. ^[18]