Apigenin suppresses PD-L1 expression in melanoma and host dendritic cells to elicit synergistic therapeutic effects.

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第一作者： Lu,Xu

第一单位： The Second Affiliated Hospital, Institute of Cancer Stem Cell, Dalian Medical University, Dalian, China.;Department of Dermatology, Second Affiliated Hospital, Dalian Medical University, Dalian, China.

作者： Lu,Xu ^[1] ; Yang,Zhang ^[2] ; Kang,Tian ^[3] ; Xi,Chen ^[4] ; Rongxin,Zhang ^[4] ; Xindi,Mu ^[4] ; Yueguang,Wu ^[5] ; Duchuang,Wang ^[5] ; Shanshan,Wang ^[5] ; Fang,Liu ^[5] ; Taishu,Wang ^[5] ; Jinrui,Zhang ^[5] ; Shuyan,Liu ^[5] ; Yingqiu,Zhang ^[5] ; Caixia,Tu ^[6] ; Han,Liu ^[7]

作者单位： The Second Affiliated Hospital, Institute of Cancer Stem Cell, Dalian Medical University, Dalian, China.;Department of Dermatology, Second Affiliated Hospital, Dalian Medical University, Dalian, China. ^[1] The Second Affiliated Hospital, Institute of Cancer Stem Cell, Dalian Medical University, Dalian, China.;Cancer Biotherapy & Translational Medicine Center of Liaoning Province, Dalian Medical University, Dalian, China. ^[2] The Second Affiliated Hospital, Institute of Cancer Stem Cell, Dalian Medical University, Dalian, China.;Department of Orthopaedics, First Affiliated Hospital, Dalian Medical University, Dalian, China. ^[3] Department of Dermatology, Second Affiliated Hospital, Dalian Medical University, Dalian, China. ^[4] The Second Affiliated Hospital, Institute of Cancer Stem Cell, Dalian Medical University, Dalian, China. ^[5] The Second Affiliated Hospital, Institute of Cancer Stem Cell, Dalian Medical University, Dalian, China. tucx2003@163.com.;Department of Dermatology, Second Affiliated Hospital, Dalian Medical University, Dalian, China. tucx2003@163.com. ^[6] The Second Affiliated Hospital, Institute of Cancer Stem Cell, Dalian Medical University, Dalian, China. liuhan@dlmedu.edu.cn.;Cancer Biotherapy & Translational Medicine Center of Liaoning Province, Dalian Medical University, Dalian, China. liuhan@dlmedu.edu.cn. ^[7]

关键词 Apigenin CD274 Flavonoid Melanoma PD-L1 STAT1