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首页> Genes and immunity> An IL7RA exon 5 polymorphism is associated with impaired IL-7Rα splicing and protection against tuberculosis in Ghana.

An IL7RA exon 5 polymorphism is associated with impaired IL-7Rα splicing and protection against tuberculosis in Ghana.

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作者： Christian,Lundtoft ^[1] ; Anthony Afum-Adjei,Awuah ^[2] ; Alptekin,Güler ^[3] ; Kirstin,Harling ^[1] ; Heiner,Schaal ^[1] ; Ertan,Mayatepek ^[4] ; Richard O,Phillips ^[1] ; Norman,Nausch ^[2] ; Ellis,Owusu-Dabo ^[3] ; Marc,Jacobsen ^[1]

作者单位： Department of General Pediatrics, Neonatology, and Pediatric Cardiology, Medical Faculty, University Children's Hospital, Duesseldorf, Germany. ^[1] Kumasi Centre for Collaborative Research in Tropical Medicine (KCCR), Kumasi, Ghana. ^[2] School of Medical Sciences, Kwame Nkrumah University of Science and Technology (KNUST), Kumasi, Ghana. ^[3] Institute of Virology, University Hospital Duesseldorf, Heinrich Heine University, Duesseldorf, Germany. ^[4] School of Public Health, Kwame Nkrumah University of Science and Technology (KNUST), Kumasi, Ghana. ^[5] Department of General Pediatrics, Neonatology, and Pediatric Cardiology, Medical Faculty, University Children's Hospital, Duesseldorf, Germany. marc.jacobsen@med.uni-duesseldorf.de. ^[6]

主题词等位基因(Alleles);选择性剪接(Alternative Splicing);CD4阳性T淋巴细胞(CD4-Positive T-Lymphocytes);外显子(Exons);加纳(Ghana);HEK293细胞(HEK293 Cells);单倍型(Haplotypes);人类(Humans);多态性, 单核苷酸(Polymorphism, Single Nucleotide);受体, 白细胞介素7(Receptors, Interleukin-7);结核(Tuberculosis)

DOI 10.1038/s41435-018-0049-5

PMID 30377306

发布时间 2022-01-29

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Genes and immunity

Genes and immunity

2019年20卷6期

514-519页

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