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Metagenomic Sequencing of HIV-1 in the Blood and Female Genital Tract Reveals Little Quasispecies Diversity during Acute Infection.

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第一作者： Anne,Piantadosi

第一单位： Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA apiantadosi@partners.org dkwon@mgh.harvard.edu.;Broad Institute, Cambridge, Massachusetts, USA.;Harvard Medical School, Boston, Massachusetts, USA.

作者： Anne,Piantadosi ^[1] ; Catherine A,Freije ^[2] ; Christina,Gosmann ^[3] ; Simon,Ye ^[4] ; Daniel,Park ^[5] ; Stephen F,Schaffner ^[6] ; Damien C,Tully ^[7] ; Todd M,Allen ^[7] ; Krista L,Dong ^[8] ; Pardis C,Sabeti ^[9] ; Douglas S,Kwon ^[10]

作者单位： Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA apiantadosi@partners.org dkwon@mgh.harvard.edu.;Broad Institute, Cambridge, Massachusetts, USA.;Harvard Medical School, Boston, Massachusetts, USA. ^[1] Broad Institute, Cambridge, Massachusetts, USA.;Ph.D. Program in Virology, Division of Medical Sciences, Harvard University, Boston, Massachusetts, USA. ^[2] Harvard Medical School, Boston, Massachusetts, USA.;Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts, USA. ^[3] Broad Institute, Cambridge, Massachusetts, USA.;Harvard-MIT Program of Health Sciences and Technology, Cambridge, Massachusetts, USA. ^[4] Broad Institute, Cambridge, Massachusetts, USA. ^[5] Broad Institute, Cambridge, Massachusetts, USA.;FAS Center for Systems Biology, Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, Massachusetts, USA.;Department of Immunology and Infectious Disease, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, USA. ^[6] Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts, USA. ^[7] Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA.;Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts, USA. ^[8] Broad Institute, Cambridge, Massachusetts, USA.;FAS Center for Systems Biology, Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, Massachusetts, USA.;Department of Immunology and Infectious Disease, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, USA.;Howard Hughes Medical Institute, Chevy Chase, Maryland, USA. ^[9] Division of Infectious Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA apiantadosi@partners.org dkwon@mgh.harvard.edu.;Harvard Medical School, Boston, Massachusetts, USA.;Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts, USA. ^[10]

关键词 bottleneck female genital tract human immunodeficiency virus metagenomic