换一批
换一批Pyridinium Oximes with Ortho-Positioned Chlorine Moiety Exhibit Improved Physicochemical Properties and Efficient Reactivation of Human Acetylcholinesterase Inhibited by Several Nerve Agents.
第一作者：
Tamara,Zorbaz
第一单位：
Institute for Medical Research and Occupational Health , Ksaverska Cesta 2 , HR-10000 Zagreb , Croatia.
作者：
主题词
乙酰胆碱酯酶(Acetylcholinesterase);丁酰胆碱酯酶(Butyrylcholinesterase);细胞系, 肿瘤(Cell Line, Tumor);化学现象(Chemical Phenomena);氯(Chlorine);胆碱酯酶抑制剂(Cholinesterase Inhibitors);胆碱酯酶再激活剂(Cholinesterase Reactivators);人类(Humans);异构现象(Isomerism);肟类(Oximes);蛋白质构象(Protein Conformation);构效关系(Structure-Activity Relationship)
DOI
10.1021/acs.jmedchem.8b01398
PMID
30383374
发布时间
2019-09-30
- 浏览2
Journal of medicinal chemistry
10753-10766页
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