Elamipretide Promotes Mitophagosome Formation and Prevents Its Reduction Induced by Nutrient Excess in INS1 β-cells.

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第一作者： Anton,Petcherski

第一单位： Departments of Medicine, Endocrinology and Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.

作者： Anton,Petcherski ^[1] ; Kyle M,Trudeau ^[2] ; Dane M,Wolf ^[3] ; Mayuko,Segawa ^[1] ; Jennifer,Lee ^[2] ; Evan P,Taddeo ^[1] ; Jude T,Deeney ^[2] ; Marc,Liesa ^[4]

作者单位： Departments of Medicine, Endocrinology and Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA. ^[1] Department of Medicine, Evans Biomedical Research Center, Boston University School of Medicine, Boston, MA 02118, USA. ^[2] Departments of Medicine, Endocrinology and Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA; Department of Medicine, Evans Biomedical Research Center, Boston University School of Medicine, Boston, MA 02118, USA. ^[3] Departments of Medicine, Endocrinology and Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA. Electronic address: mliesa@mednet.ucla.edu. ^[4]

关键词 SS-31 elamipretide lipotoxicity mitochondria mitophagy β-cells