换一批5-lipoxygenase-dependent biosynthesis of novel 20:4 n-3 metabolites with anti-inflammatory activity.
第一作者：
K J,Gagnon
第一单位：
Départment de Chimie et Biochimie, Université de Moncton, 18 Antonine-Maillet Avenue, Moncton, NB E1A 3E9, Canada.
作者：
关键词
AA, arachidonic acidADA, adenosine deaminaseALA, alpha-linolenic acidAbbreviations: 19-OH-PGB(2), 19(R)-hydroxy-prostaglandin B(2)BLT1, leukotriene B(4) receptor 1DHA, docosahexaenoic acidDPA, docosapentaenoic acidETA, eicosatetraenoic acidEicosanoidsEtOH, ethanolHpETE, hydroperoxyeicosatetraenoic acidInflammationLO, lipoxygenaseLTA(4), leukotriene A(4)LTB(4), leukotriene B(4)LTC(4), leukotriene C(4)LeukotrienesLipid mediatorsMeOH, methanolNEM, N-ethylmaleimideNeutrophilsRP-HPLC, reverse phase-HPLCSDA, stearidonic acid
医学主题词
消炎药(Anti-Inflammatory Agents);花生四烯酸盐5-脂氧合酶(Arachidonate 5-Lipoxygenase);花生四烯酸(Arachidonic Acid);二十碳五烯酸(Eicosapentaenoic Acid);女(雌)性(Female);HEK293细胞(HEK293 Cells);人类(Humans);羟基花生四烯酸类(Hydroxyeicosatetraenoic Acids);白三烯B4(Leukotriene B4);男(雄)性(Male);中性白细胞(Neutrophils)
DOI
10.1016/j.plefa.2018.10.005
PMID
30392579
发布时间
2020-01-16
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