MORC2 promotes development of an aggressive colorectal cancer phenotype through inhibition of NDRG1.
作者:
主题词
老年人(Aged);动物(Animals);细胞周期蛋白质类(Cell Cycle Proteins);细胞系, 肿瘤(Cell Line, Tumor);结直肠肿瘤(Colorectal Neoplasms);女(雌)性(Female);基因表达谱(Gene Expression Profiling);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);HEK293细胞(HEK293 Cells);HT29细胞(HT29 Cells);人类(Humans);细胞内信号肽和蛋白质类(Intracellular Signaling Peptides and Proteins);淋巴转移(Lymphatic Metastasis);男(雄)性(Male);小鼠, 近交BALB C(Mice, Inbred BALB C);小鼠, 裸(Mice, Nude);中年人(Middle Aged);表型(Phenotype);RNA干扰(RNA Interference);转录因子(Transcription Factors);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays)
DOI
10.1111/cas.13863
PMID
30407715
发布时间
2021-01-09
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Cancer science
135-146页
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