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Mycobacterium Tuberculosis and Interactions with the Host Immune System: Opportunities for Nanoparticle Based Immunotherapeutics and Vaccines.

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第一作者： Raymonde B,Bekale

第一单位： Discipline of Pharmaceutics, School of Pharmacy, University of the Western Cape, Cape Town, South Africa.

作者： Raymonde B,Bekale ^[1] ; Su-Mari,Du Plessis ^[2] ; Nai-Jen,Hsu ^[3] ; Jyoti R,Sharma ^[4] ; Samantha L,Sampson ^[2] ; Muazzam,Jacobs ^[5] ; Mervin,Meyer ^[6] ; Gene D,Morse ^[7] ; Admire,Dube ^[8]

作者单位： Discipline of Pharmaceutics, School of Pharmacy, University of the Western Cape, Cape Town, South Africa. ^[1] NRF-DST Centre of Excellence for Biomedical Tuberculosis Research, South African Medical Research Council Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa. ^[2] Division of Immunology, Department of Pathology, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa. ^[3] National Health Laboratory Service, Johannesburg, South Africa. ^[4] Division of Immunology, Department of Pathology, Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.;National Health Laboratory Service, Johannesburg, South Africa.;Immunology of Infectious Disease Research Unit, South African Medical Research Council, Cape Town, South Africa. ^[5] DST/Mintek Nanotechnology Innovation Centre (NIC), Biolabels Unit, Department of Biotechnology, University of the Western Cape (UWC), Cape Town, South Africa. ^[6] AIDS Clinical Trials Group Pharmacology Specialty Laboratory, New York State Center of Excellence in Bioinformatics and Life Sciences, School of Pharmacy and Pharmaceutical Sciences, University at Buffalo, Buffalo, New York, USA. ^[7] Discipline of Pharmaceutics, School of Pharmacy, University of the Western Cape, Cape Town, South Africa. adube@uwc.ac.za. ^[8]

关键词 Mycobacterium tuberculosis immunotherapeutic nanoparticles immunotherapy for tuberculosis nanoparticle based host directed therapy nanoparticles and vaccination