Pharmacokinetic-pharmacodynamic modelling of platelet response to ticagrelor in stable coronary artery disease and prior myocardial infarction patients.
第一作者:
Magnus,Åstrand
第一单位:
Early Clinical Development, IMED Biotech Unit, AstraZeneca, Gothenburg, Sweden.
作者:
医学主题词
成年人(Adult);老年人(Aged);老年人, 80以上(Aged, 80 and over);血小板(Blood Platelets);临床试验, Ⅱ期(主题)(Clinical Trials, Phase II as Topic);临床试验, Ⅲ期(主题)(Clinical Trials, Phase III as Topic);冠状动脉疾病(Coronary Artery Disease);剂量效应关系, 药物(Dose-Response Relationship, Drug);用药计划表(Drug Administration Schedule);女(雌)性(Female);人类(Humans);男(雄)性(Male);中年人(Middle Aged);模型, 生物学(Models, Biological);多中心研究(主题)(Multicenter Studies as Topic);心肌梗死(Myocardial Infarction);血小板聚集(Platelet Aggregation);血小板功能试验(Platelet Function Tests);嘌呤能P2Y受体拮抗剂(Purinergic P2Y Receptor Antagonists);随机对照试验(主题)(Randomized Controlled Trials as Topic);治疗结果(Treatment Outcome);青年人(Young Adult)
DOI
10.1111/bcp.13812
PMID
30414387
发布时间
2021-01-09
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