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首页> Clinical cardiology> Design of the randomized, placebo-controlled evolocumab for early reduction of LDL-cholesterol levels in patients with acute coronary syndromes (EVOPACS) trial.

Design of the randomized, placebo-controlled evolocumab for early reduction of LDL-cholesterol levels in patients with acute coronary syndromes (EVOPACS) trial.

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作者： Konstantinos C,Koskinas ^[1] ; Stephan,Windecker ^[1] ; Aliki,Buhayer ^[2] ; Baris,Gencer ^[3] ; Giovanni,Pedrazzini ^[4] ; Christian,Mueller ^[5] ; Stephan,Cook ^[6] ; Olivier,Muller ^[7] ; Christian M,Matter ^[8] ; Lorenz,Räber ^[1] ; Dik,Heg ^[9] ; François,Mach ^[3] ; EVOPACS Investigators

作者单位： Department of Cardiology, Bern University Hospital, Bern, Switzerland. ^[1] PRISM Scientific Sàrl, Switzerland. ^[2] Department of Cardiology, Geneva University Hospital, Geneva, Switzerland. ^[3] Cardiocentro, Lugano, Switzerland. ^[4] Department of Cardiology and Cardiovascular Research Institute Basel, University Hospital Basel, Basel, Switzerland. ^[5] Department of Cardiology, Fribourg Hospital and University, Fribourg, Switzerland. ^[6] Service of Cardiology, Lausanne University Hospital, Lausanne, Switzerland. ^[7] Department of Cardiology, University Heart Center, University Hospital Zurich, Zurich, Switzerland. ^[8] CTU Bern, University of Bern, Bern, Switzerland. ^[9]

关键词 PCSK9 inhibitor acute coronary syndrome lipidology

主题词急性冠状动脉综合征(Acute Coronary Syndrome);抗体, 单克隆(Antibodies, Monoclonal);抗胆固醇血症药(Anticholesteremic Agents);胆固醇, LDL(Cholesterol, LDL);剂量效应关系, 药物(Dose-Response Relationship, Drug);双盲法(Double-Blind Method);可行性研究(Feasibility Studies);女(雌)性(Female);随访研究(Follow-Up Studies);人类(Humans);高胆固醇血症(Hypercholesterolemia);男(雄)性(Male);中年人(Middle Aged);前瞻性研究(Prospective Studies);时间因素(Time Factors);治疗结果(Treatment Outcome)

DOI 10.1002/clc.23112

PMID 30421481

发布时间 2021-01-09

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Clinical cardiology

Clinical cardiology

2018年41卷12期

1513-1520页

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Clinical cardiology

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2018年41卷12期

1513-1520页

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