Detailed Characterization of Early HIV-1 Replication Dynamics in Primary Human Macrophages.

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作者： David Alejandro,Bejarano ^[1] ; Maria C,Puertas ^[2] ; Kathleen,Börner ^[3] ; Javier,Martinez-Picado ^[4] ; Barbara,Müller ^[5] ; Hans-Georg,Kräusslich ^[6]

作者单位： Department of Infectious Diseases, Virology, University of Heidelberg, 69120 Heidelberg, Germany. david.bejarano@med.uni-heidelberg.de. ^[1] AIDS Research Institute IrsiCaixa, Institut d'Investigació en Cièncias de la Salut Germans Trias i Pujol, Universitat Autònoma de Barcelona, 08916 Badalona, Spain. mcpuertas@irsicaixa.es. ^[2] Department of Infectious Diseases, Virology, University of Heidelberg, 69120 Heidelberg, Germany. kathleen.boerner@bioquant.uni-heidelberg.de. ^[3] German Center for Infection Research, Partner Site Heidelberg, 69120 Heidelberg, Germany. kathleen.boerner@bioquant.uni-heidelberg.de. ^[4] AIDS Research Institute IrsiCaixa, Institut d'Investigació en Cièncias de la Salut Germans Trias i Pujol, Universitat Autònoma de Barcelona, 08916 Badalona, Spain. jmpicado@irsicaixa.es. ^[5] Faculty of Medicine, University of Vic-Central University of Catalonia (UVic-UCC), 08500 Vic, Spain. jmpicado@irsicaixa.es. ^[6] Catalan Institution for Research and Advanced Studies (ICREA), 08010 Barcelona, Spain. jmpicado@irsicaixa.es. ^[7] Department of Infectious Diseases, Virology, University of Heidelberg, 69120 Heidelberg, Germany. barbara.mueller@med.uni-heidelberg.de. ^[8] Department of Infectious Diseases, Virology, University of Heidelberg, 69120 Heidelberg, Germany. hans-georg.kraeusslich@med.uni-heidelberg.de. ^[9] German Center for Infection Research, Partner Site Heidelberg, 69120 Heidelberg, Germany. hans-georg.kraeusslich@med.uni-heidelberg.de. ^[10]

关键词 SAMHD1 human immunodeficiency virus pre-integration complex primary macrophages replication kinetics reverse-transcription complex