Microwave-Assisted Expeditious Synthesis of 2-Alkyl-2-(<i>N</i>-arylsulfonylindol-3-yl)-3-<i>N</i>-acyl-5-aryl-1,3,4-oxadiazolines Catalyzed by HgCl₂ under Solvent-Free Conditions as Potential Anti-HIV-1 Agents.

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第一作者： Zhiping,Che

第一单位： Laboratory of Pharmaceutical Design & Synthesis, Department of Plant Protection, College of Forestry, Henan University of Science and Technology, Luoyang 471003, China. zhipingche@163.com.

作者： Zhiping,Che ^[1] ; Yuee,Tian ^[2] ; Shengming,Liu ^[3] ; Jia,Jiang ^[4] ; Mei,Hu ^[5] ; Genqiang,Chen ^[6]

作者单位： Laboratory of Pharmaceutical Design & Synthesis, Department of Plant Protection, College of Forestry, Henan University of Science and Technology, Luoyang 471003, China. zhipingche@163.com. ^[1] Laboratory of Pharmaceutical Design & Synthesis, Department of Plant Protection, College of Forestry, Henan University of Science and Technology, Luoyang 471003, China. tianyuee1985@163.com. ^[2] Laboratory of Pharmaceutical Design & Synthesis, Department of Plant Protection, College of Forestry, Henan University of Science and Technology, Luoyang 471003, China. zhenxiziji2005@126.com. ^[3] Laboratory of Pharmaceutical Design & Synthesis, Department of Plant Protection, College of Forestry, Henan University of Science and Technology, Luoyang 471003, China. lxy_jiangjia@126.com. ^[4] Laboratory of Pharmaceutical Design & Synthesis, Department of Plant Protection, College of Forestry, Henan University of Science and Technology, Luoyang 471003, China. lxy_humei@163.com. ^[5] Laboratory of Pharmaceutical Design & Synthesis, Department of Plant Protection, College of Forestry, Henan University of Science and Technology, Luoyang 471003, China. genqiangchen@126.com. ^[6]

关键词 1,3,4-oxadiazolines HgCl2 catalyst anti-HIV-1 activity microwave irradiation

主题词抗HIV药(Anti-HIV Agents);催化作用(Catalysis);HIV-1(HIV-1);升汞(Mercuric Chloride);微生物敏感性试验(Microbial Sensitivity Tests);恶二唑类(Oxadiazoles);溶剂(Solvents)

DOI 10.3390/molecules23112936

PMID 30423803

发布时间 2023-11-04

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