Dysregulation of autophagy and stress granule-related proteins in stress-driven Tau pathology.

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作者： Joana Margarida,Silva ^[1] ; Sara,Rodrigues ^[1] ; Belém,Sampaio-Marques ^[1] ; Patrícia,Gomes ^[1] ; Andreia,Neves-Carvalho ^[1] ; Chrysoula,Dioli ^[1] ; Carina,Soares-Cunha ^[1] ; Brandon F,Mazuik ^[2] ; Akihiko,Takashima ^[3] ; Paula,Ludovico ^[1] ; Benjamin,Wolozin ^[2] ; Nuno,Sousa ^[1] ; Ioannis,Sotiropoulos ^[4]

作者单位： Life and Health Sciences Research Institute (ICVS), Medical School, University of Minho, Campus Gualtar, 4710-057, Braga, Portugal.;ICVS/3B's-PT Government Associate Laboratory, Braga/Guimarães, Portugal. ^[1] Department of Pharmacology & Experimental Therapeutics, School of Medicine, Boston University, MA, 02118, Boston, USA. ^[2] Department of Life Science, Faculty of Science, Gakushuin University, 171-8588, Tokyo, Japan. ^[3] Life and Health Sciences Research Institute (ICVS), Medical School, University of Minho, Campus Gualtar, 4710-057, Braga, Portugal. ioannis@med.uminho.pt.;ICVS/3B's-PT Government Associate Laboratory, Braga/Guimarães, Portugal. ioannis@med.uminho.pt. ^[4]

主题词阿尔茨海默病(Alzheimer Disease);动物(Animals);自噬(Autophagy);热休克蛋白质类(Heat-Shock Proteins);小鼠, 转基因(Mice, Transgenic);tau蛋白质类(tau Proteins)

DOI 10.1038/s41418-018-0217-1

PMID 30442948

发布时间 2024-07-20

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