Structure-activity relationships for highly potent half-sandwich organoiridium(III) anticancer complexes with C^N-chelated ligands.

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作者： Yuliang,Yang ^[1] ; Lihua,Guo ^[2] ; Xingxing,Ge ^[1] ; Shaopeng,Shi ^[1] ; Yuteng,Gong ^[1] ; Zhishan,Xu ^[3] ; Xiaofeng,Zheng ^[1] ; Zhe,Liu ^[4]

作者单位： Institute of Anticancer Agents Development and Theranostic Application, The Key Laboratory of Life-Organic Analysis and Key Laboratory of Pharmaceutical Intermediates and Analysis of Natural Medicine, Department of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, China. ^[1] Institute of Anticancer Agents Development and Theranostic Application, The Key Laboratory of Life-Organic Analysis and Key Laboratory of Pharmaceutical Intermediates and Analysis of Natural Medicine, Department of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, China. Electronic address: guolihua@qfnu.edu.cn. ^[2] Institute of Anticancer Agents Development and Theranostic Application, The Key Laboratory of Life-Organic Analysis and Key Laboratory of Pharmaceutical Intermediates and Analysis of Natural Medicine, Department of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, China; Department of Chemistry and Chemical Engineering, Shandong Normal University, Jinan 250014, China. ^[3] Institute of Anticancer Agents Development and Theranostic Application, The Key Laboratory of Life-Organic Analysis and Key Laboratory of Pharmaceutical Intermediates and Analysis of Natural Medicine, Department of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, China. Electronic address: liuzheqd@163.com. ^[4]

关键词 Anticancer Half-sandwich Imine-N-heterocyclic carbene Iridium(III) complexes Structure-activity relationships