Metabolic imaging with the use of fluorescence lifetime imaging microscopy (FLIM) accurately detects mitochondrial dysfunction in mouse oocytes.-论文-万方医学网

作者： Tim,Sanchez ^[1] ; Tianren,Wang ^[2] ; Marta Venturas,Pedro ^[1] ; Man,Zhang ^[2] ; Ecem,Esencan ^[2] ; Denny,Sakkas ^[3] ; Dan,Needleman ^[1] ; Emre,Seli ^[4]

作者单位： Departments of Applied Physics and Molecular and Cellular Biology, Harvard University, Cambridge, Massachusetts. ^[1] Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University, New Haven, Connecticut. ^[2] Boston IVF, Waltham, Massachusetts. ^[3] Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale University, New Haven, Connecticut. Electronic address: emre.seli@yale.edu. ^[4]

主题词动物(Animals);细胞, 培养的(Cells, Cultured);计算机系统(Computer Systems);胚胎培养技术(Embryo Culture Techniques);胚胎, 哺乳动物(Embryo, Mammalian);胚胎发育(Embryonic Development);内肽酶Clp(Endopeptidase Clp);女(雌)性(Female);黄素腺嘌呤二核苷酸(Flavin-Adenine Dinucleotide);荧光(Fluorescence);男(雄)性(Male);母亲年龄(Maternal Age);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 基因敲除(Mice, Knockout);显微镜检查, 荧光(Microscopy, Fluorescence);线粒体(Mitochondria);分子显像(Molecular Imaging);NAD(NAD);卵母细胞(Oocytes);活性氧(Reactive Oxygen Species)

DOI 10.1016/j.fertnstert.2018.07.022

PMID 30446247

发布时间 2019-12-10

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Metabolic imaging with the use of fluorescence lifetime imaging microscopy (FLIM) accurately detects mitochondrial dysfunction in mouse oocytes.

Fertility and sterility

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Fertility and sterility

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Metabolic imaging with the use of fluorescence lifetime imaging microscopy (FLIM) accurately detects mitochondrial dysfunction in mouse oocytes.

Fertility and sterility

相似文献

Fertility and sterility

相关期刊

检索历史清除