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首页> The Prostate> Germline genetic testing for inherited prostate cancer in practice: Implications for genetic testing, precision therapy, and cascade testing.

Germline genetic testing for inherited prostate cancer in practice: Implications for genetic testing, precision therapy, and cascade testing.

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作者： Veda N,Giri ^[1] ; Sarah E,Hegarty ^[2] ; Colette,Hyatt ^[1] ; Erin,O'Leary ^[3] ; John,Garcia ^[3] ; Karen E,Knudsen ^[4] ; William K,Kelly ^[5] ; Leonard G,Gomella ^[6]

作者单位： Cancer Risk Assessment and Clinical Cancer Genetics, Division of Population Science, Department of Medical Oncology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania. ^[1] Division of Biostatistics, Department of Pharmacology and Experimental Therapeutics, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania. ^[2] Invitae, San Francisco, California. ^[3] Department of Cancer Biology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania. ^[4] Division of Solid Tumor Oncology, Department of Medical Oncology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania. ^[5] Department of Urology, Thomas Jefferson University, Philadelphia, Pennsylvania. ^[6]

关键词 DNA repair cascade testing family history genetic testing prostate cancer

主题词 BRCA1蛋白质(BRCA1 Protein);BRCA2蛋白质(BRCA2 Protein);乳腺肿瘤(Breast Neoplasms);横断面研究(Cross-Sectional Studies);DNA修复(DNA Repair);女(雌)性(Female);基因检测(Genetic Testing);遗传变异(Genetic Variation);生殖细胞(Germ Cells);人类(Humans);男(雄)性(Male);中年人(Middle Aged);前列腺肿瘤(Prostatic Neoplasms);回顾性研究(Retrospective Studies)

DOI 10.1002/pros.23739

PMID 30450585

发布时间 2019-11-18

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The Prostate

The Prostate

2019年79卷4期

333-339页

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