Hyperglycemia aggravates microenvironment hypoxia and promotes the metastatic ability of pancreatic cancer.

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第一作者： Wei,Li

第一单位： Department of Hepatobiliary Surgery, First Affiliated Hospital of Xi'an Jiaotong University, 277 West Yanta Road, Xi'an 710061, China.

作者： Wei,Li ^[1] ; Han,Liu ^[2] ; Weikun,Qian ^[1] ; Liang,Cheng ^[1] ; Bin,Yan ^[1] ; Liang,Han ^[1] ; Qinhong,Xu ^[1] ; Qingyong,Ma ^[1] ; Jiguang,Ma ^[3]

作者单位： Department of Hepatobiliary Surgery, First Affiliated Hospital of Xi'an Jiaotong University, 277 West Yanta Road, Xi'an 710061, China. ^[1] Department of Hepatobiliary Surgery, Qilu Hospital of Shandong University, Shandong 250012, China. ^[2] Department of Anesthesiology, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, China. ^[3]

关键词 CCL2, chemical chemokine 2 CoCl2, cobalt chloride ECM, endothelial cells, extracellular matrix EGF, epidermal growth factor EMT, epithelial-mesenchymal transition GDNF, glial cell line-derived neurotrophic factor H2O2, hydrogen peroxide HIF-1α HIF-1α, hypoxia-inducible factor 1α Hyperglycemia Hypoxia Metastasis PNI, perineural invasion PSC, pancreatic stellate cells Pancreatic cancer SOD, superoxide dismutase STZ, streptozotocin TEM, transmission electron microscopy VEGF, vascular endothelial growth factor

DOI 10.1016/j.csbj.2018.10.006

PMID 30455857

发布时间 2022-03-30

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Computational and structural biotechnology journal

2018年16卷

479-487页

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Hyperglycemia aggravates microenvironment hypoxia and promotes the metastatic ability of pancreatic cancer.

Computational and structural biotechnology journal

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Computational and structural biotechnology journal

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Hyperglycemia aggravates microenvironment hypoxia and promotes the metastatic ability of pancreatic cancer.

Computational and structural biotechnology journal

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Computational and structural biotechnology journal

相关期刊

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