Reduction of matrix metalloproteinase 9 (MMP-9) protects motor neurons from TDP-43-triggered death in rNLS8 mice.
第一作者:
Krista J,Spiller
第一单位:
Center for Neurodegenerative Disease Research, Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: spillerk@upenn.edu.
作者:
主题词
肌萎缩侧索硬化(Amyotrophic Lateral Sclerosis);动物(Animals);DNA结合蛋白质类(DNA-Binding Proteins);疾病模型, 动物(Disease Models, Animal);女(雌)性(Female);基因敲低技术(Gene Knockdown Techniques);男(雄)性(Male);基质金属蛋白酶9(Matrix Metalloproteinase 9);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 转基因(Mice, Transgenic);运动神经元(Motor Neurons);肌, 骨骼(Muscle, Skeletal)
DOI
10.1016/j.nbd.2018.11.013
PMID
30458231
发布时间
2022-01-20
- 浏览40
Neurobiology of disease
133-140页
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